| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| propafenone | beta-1 adrenergic receptor | small molecule | NA | drugbank , DGIDB | Cardiac Arrhythmia[MeSHID:D001145] Heart Diseases[MeSHID:D006331] Heart Ventricle[MeSHID:D006352] Tachycardia Ventricular[MeSHID:D017180] Atrial Fibrillation[MeSHID:D001281] Recurrence (disease attribute)[MeSHID:D012008] Tachyarrhythmia[MeSHID:D013610] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.13 | approved | antagonist |
| propafenone | beta-2 adrenergic receptor | small molecule | NA | drugbank , DGIDB | Cardiac Arrhythmia[MeSHID:D001145] Heart Diseases[MeSHID:D006331] Heart Ventricle[MeSHID:D006352] Tachycardia Ventricular[MeSHID:D017180] Atrial Fibrillation[MeSHID:D001281] Recurrence (disease attribute)[MeSHID:D012008] Tachyarrhythmia[MeSHID:D013610] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.08 | approved | antagonist |
| propafenone | potassium voltage-gated channel subfamily h member 2 | small molecule | NA | drugbank , DGIDB | Cardiac Arrhythmia[MeSHID:D001145] Heart Diseases[MeSHID:D006331] Heart Ventricle[MeSHID:D006352] Tachycardia Ventricular[MeSHID:D017180] Atrial Fibrillation[MeSHID:D001281] Recurrence (disease attribute)[MeSHID:D012008] Tachyarrhythmia[MeSHID:D013610] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.12 | approved | inhibitor |
| propafenone | e3 ubiquitin-protein ligase cop1 | NA | Successful target | TTD | Cardiac Arrhythmia[MeSHID:D001145] Heart Diseases[MeSHID:D006331] Heart Ventricle[MeSHID:D006352] Tachycardia Ventricular[MeSHID:D017180] Atrial Fibrillation[MeSHID:D001281] Recurrence (disease attribute)[MeSHID:D012008] Tachyarrhythmia[MeSHID:D013610] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | unknown |
| propafenone | sodium channel protein type 5 subunit alpha | small molecule | NA | drugbank , DGIDB | Cardiac Arrhythmia[MeSHID:D001145] Heart Diseases[MeSHID:D006331] Heart Ventricle[MeSHID:D006352] Tachycardia Ventricular[MeSHID:D017180] Atrial Fibrillation[MeSHID:D001281] Recurrence (disease attribute)[MeSHID:D012008] Tachyarrhythmia[MeSHID:D013610] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.39 | approved | inhibitor |
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