Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
progesterone androgen receptor small molecule NA drugbank , DGIDB Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 0 approved,vet_approved agonist,potentiator
progesterone androgen receptor small molecule NA drugbank , DGIDB Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Premature Obstetric Labor[MeSHID:D007752]		 0 approved,vet_approved agonist,potentiator
progesterone steroid 17-alpha-hydroxylase/17,20 lyase small molecule NA drugbank Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 NA approved,vet_approved substrate,inhibitor
progesterone steroid 17-alpha-hydroxylase/17,20 lyase small molecule NA drugbank Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Premature Obstetric Labor[MeSHID:D007752]		 NA approved,vet_approved substrate,inhibitor
progesterone estrogen receptor alpha small molecule NA drugbank , DGIDB Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 0.04 approved,vet_approved agonist,inhibitor,downregulator
progesterone estrogen receptor alpha small molecule NA drugbank , DGIDB Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Premature Obstetric Labor[MeSHID:D007752]		 0.04 approved,vet_approved agonist,inhibitor,downregulator
progesterone estrogen receptor beta small molecule NA drugbank Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 NA approved,vet_approved agonist,downregulator
progesterone estrogen receptor beta small molecule NA drugbank Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Premature Obstetric Labor[MeSHID:D007752]		 NA approved,vet_approved agonist,downregulator
progesterone glucocorticoid receptor small molecule NA drugbank , DGIDB Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Premature Obstetric Labor[MeSHID:D007752]		 0.03 approved,vet_approved partial agonist
progesterone glucocorticoid receptor small molecule NA drugbank , DGIDB Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 0.03 approved,vet_approved partial agonist
progesterone mineralocorticoid receptor small molecule NA drugbank , DGIDB Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Premature Obstetric Labor[MeSHID:D007752]		 0.23 approved,vet_approved antagonist,agonist
progesterone mineralocorticoid receptor small molecule NA drugbank , DGIDB Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 0.23 approved,vet_approved antagonist,agonist
progesterone kappa-type opioid receptor small molecule NA drugbank Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 NA approved,vet_approved activator,potentiator
progesterone kappa-type opioid receptor small molecule NA drugbank Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Premature Obstetric Labor[MeSHID:D007752]		 NA approved,vet_approved activator,potentiator
progesterone alpha-1-acid glycoprotein 1 small molecule NA drugbank Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Premature Obstetric Labor[MeSHID:D007752]		 NA approved,vet_approved binder
progesterone alpha-1-acid glycoprotein 1 small molecule NA drugbank Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 NA approved,vet_approved binder
progesterone progesterone receptor small molecule Successful target TTD , drugbank , DGIDB Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Premature Obstetric Labor[MeSHID:D007752]		 0.22 approved,vet_approved agonist
progesterone progesterone receptor small molecule Successful target TTD , drugbank , DGIDB Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 0.22 approved,vet_approved agonist
progesterone sex hormone-binding globulin small molecule NA drugbank Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Coronavirus Infections[MeSHID:D018352]
Disease[MeSHID:D004194]		 NA approved,vet_approved binder,potentiator
progesterone sex hormone-binding globulin small molecule NA drugbank Blastocyst Implantation
natural[MeSHID:D010064]
Vagina[MeSHID:D014621]
Attention[MeSHID:D001288]
Fibroid Tumor[MeSHID:D007889]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Female infertility[MeSHID:D007247]
Endometrial Hyperplasia[MeSHID:D004714]
Uterine Cancer[MeSHID:D014594]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Malnutrition[MeSHID:D044342]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Premature Obstetric Labor[MeSHID:D007752]		 NA approved,vet_approved binder,potentiator
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