| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| primidone | neuronal acetylcholine receptor subunit alpha-4 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.24 | approved,vet_approved | antagonist |
| primidone | neuronal acetylcholine receptor subunit alpha-7 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.23 | approved,vet_approved | antagonist |
| primidone | gaba(a) receptor alpha-1 | NA | Successful target | TTD , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.25 | approved | positive modulator |
| primidone | gaba(a) receptor alpha-1 | NA | Successful target | TTD , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.25 | approved | unknown |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.25 | approved,vet_approved | positive allosteric modulator,positive modulator |
| primidone | gamma-aminobutyric acid receptor subunit alpha-1 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.25 | approved,vet_approved | potentiator,positive modulator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.25 | approved,vet_approved | positive allosteric modulator |
| primidone | gamma-aminobutyric acid receptor subunit alpha-1 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.25 | approved,vet_approved | potentiator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.12 | approved,vet_approved | positive allosteric modulator |
| primidone | gamma-aminobutyric acid receptor subunit alpha-2 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.12 | approved,vet_approved | potentiator,positive modulator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.12 | approved,vet_approved | positive allosteric modulator,positive modulator |
| primidone | gamma-aminobutyric acid receptor subunit alpha-2 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.12 | approved,vet_approved | potentiator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.12 | approved,vet_approved | positive allosteric modulator |
| primidone | gamma-aminobutyric acid receptor subunit alpha-3 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.12 | approved,vet_approved | potentiator |
| primidone | gamma-aminobutyric acid receptor subunit alpha-3 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.12 | approved,vet_approved | potentiator,positive modulator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.12 | approved,vet_approved | positive allosteric modulator,positive modulator |
| primidone | gamma-aminobutyric acid receptor subunit alpha-4 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.11 | approved,vet_approved | potentiator,positive modulator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.11 | approved,vet_approved | positive allosteric modulator,positive modulator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.11 | approved,vet_approved | positive allosteric modulator |
| primidone | gamma-aminobutyric acid receptor subunit alpha-4 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.11 | approved,vet_approved | potentiator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.12 | approved,vet_approved | positive allosteric modulator,positive modulator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.12 | approved,vet_approved | positive allosteric modulator |
| primidone | gamma-aminobutyric acid receptor subunit alpha-5 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.12 | approved,vet_approved | potentiator,positive modulator |
| primidone | gamma-aminobutyric acid receptor subunit alpha-5 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.12 | approved,vet_approved | potentiator |
| primidone | gamma-aminobutyric acid receptor subunit alpha-6 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.13 | approved,vet_approved | potentiator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.13 | approved,vet_approved | positive allosteric modulator,positive modulator |
| primidone | gamma-aminobutyric acid receptor subunit alpha-6 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.13 | approved,vet_approved | potentiator,positive modulator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.13 | approved,vet_approved | positive allosteric modulator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.03 | approved,vet_approved | positive allosteric modulator,positive modulator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.03 | approved,vet_approved | positive allosteric modulator,positive modulator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.03 | approved,vet_approved | positive allosteric modulator,positive modulator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.03 | approved,vet_approved | positive allosteric modulator,positive modulator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.03 | approved,vet_approved | positive allosteric modulator,positive modulator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.03 | approved,vet_approved | positive allosteric modulator,positive modulator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.03 | approved,vet_approved | positive allosteric modulator,positive modulator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.03 | approved,vet_approved | positive allosteric modulator,positive modulator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.03 | approved,vet_approved | positive allosteric modulator,positive modulator |
| primidone | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.04 | approved,vet_approved | positive allosteric modulator,positive modulator |
| primidone | glutamate receptor 2 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.24 | approved,vet_approved | antagonist |
| primidone | glutamate receptor ionotropic, kainate 2 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Essential Tremor[MeSHID:D020329] Epilepsies Partial[MeSHID:D004828] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] |
0.53 | approved,vet_approved | antagonist |
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