Drug-Target Information | ||||||||
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Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
pravastatin | histone deacetylase 2 | small molecule | NA | drugbank | Serum[MeSHID:D044967] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Myocardial Infarction[MeSHID:D009203] Transient Cerebral Ischemia[MeSHID:D002546] Disease Progression[MeSHID:D018450] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Hypercholesterolemia[MeSHID:D006937] Diet therapy[MeSHID:D004035] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Blood[MeSHID:D001769] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Cardiac Death[MeSHID:D003643] Premature Birth[MeSHID:D047928] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Term Birth[MeSHID:D047929] Coronary Arteriosclerosis[MeSHID:D003324] Hypercholesterolemia Familial[MeSHID:D006938] Disease[MeSHID:D004194] Myocardium[MeSHID:D009206] Hyperlipoproteinemia Type IV[MeSHID:D006953] Hyperlipoproteinemia Type III[MeSHID:D006952] Risk Reduction[MeSHID:D040242] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
pravastatin | hmg-coa reductase | NA | Successful target | TTD , DGIDB | Serum[MeSHID:D044967] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Myocardial Infarction[MeSHID:D009203] Transient Cerebral Ischemia[MeSHID:D002546] Disease Progression[MeSHID:D018450] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Hypercholesterolemia[MeSHID:D006937] Diet therapy[MeSHID:D004035] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Blood[MeSHID:D001769] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Cardiac Death[MeSHID:D003643] Premature Birth[MeSHID:D047928] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Term Birth[MeSHID:D047929] Coronary Arteriosclerosis[MeSHID:D003324] Hypercholesterolemia Familial[MeSHID:D006938] Disease[MeSHID:D004194] Myocardium[MeSHID:D009206] Hyperlipoproteinemia Type IV[MeSHID:D006953] Hyperlipoproteinemia Type III[MeSHID:D006952] Risk Reduction[MeSHID:D040242] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.27 | approved | unknown |
pravastatin | 3-hydroxy-3-methylglutaryl-coenzyme a reductase | small molecule | NA | drugbank , DGIDB | Serum[MeSHID:D044967] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Myocardial Infarction[MeSHID:D009203] Transient Cerebral Ischemia[MeSHID:D002546] Disease Progression[MeSHID:D018450] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Hypercholesterolemia[MeSHID:D006937] Diet therapy[MeSHID:D004035] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Blood[MeSHID:D001769] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Cardiac Death[MeSHID:D003643] Premature Birth[MeSHID:D047928] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Term Birth[MeSHID:D047929] Coronary Arteriosclerosis[MeSHID:D003324] Hypercholesterolemia Familial[MeSHID:D006938] Disease[MeSHID:D004194] Myocardium[MeSHID:D009206] Hyperlipoproteinemia Type IV[MeSHID:D006953] Hyperlipoproteinemia Type III[MeSHID:D006952] Risk Reduction[MeSHID:D040242] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.27 | approved | inhibitor |
pravastatin | hmg-coa reductase | NA | Successful target | TTD , DGIDB | Serum[MeSHID:D044967] Cardiovascular Diseases[MeSHID:D002318] Arteriosclerosis[MeSHID:D001161] Myocardial Infarction[MeSHID:D009203] Transient Cerebral Ischemia[MeSHID:D002546] Disease Progression[MeSHID:D018450] Dyslipidemias[MeSHID:D050171] Hypertriglyceridemia[MeSHID:D015228] Hypercholesterolemia[MeSHID:D006937] Diet therapy[MeSHID:D004035] Coronary heart disease[MeSHID:D003327] Hyperlipidemia[MeSHID:D006949] Blood[MeSHID:D001769] Plasma[MeSHID:D010949] Cerebrovascular accident[MeSHID:D020521] Cardiac Death[MeSHID:D003643] Premature Birth[MeSHID:D047928] Heart[MeSHID:D006321] Atherosclerosis[MeSHID:D050197] Heterozygote[MeSHID:D006579] Term Birth[MeSHID:D047929] Coronary Arteriosclerosis[MeSHID:D003324] Hypercholesterolemia Familial[MeSHID:D006938] Disease[MeSHID:D004194] Myocardium[MeSHID:D009206] Hyperlipoproteinemia Type IV[MeSHID:D006953] Hyperlipoproteinemia Type III[MeSHID:D006952] Risk Reduction[MeSHID:D040242] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.27 | approved | inhibitor |
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