Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
pramipexole alpha-2a adrenergic receptor small molecule NA drugbank Secondary Parkinson Disease[MeSHID:D010302]
Restless Legs Syndrome[MeSHID:D012148]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Parkinson Disease[MeSHID:D010300]		 NA approved,investigational agonist
pramipexole dopamine d2 receptor small molecule Successful target TTD , drugbank , DGIDB Secondary Parkinson Disease[MeSHID:D010302]
Restless Legs Syndrome[MeSHID:D012148]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Parkinson Disease[MeSHID:D010300]		 1.2 approved,investigational agonist
pramipexole dopamine d3 receptor small molecule Successful target TTD , drugbank , DGIDB Secondary Parkinson Disease[MeSHID:D010302]
Restless Legs Syndrome[MeSHID:D012148]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Parkinson Disease[MeSHID:D010300]		 3.17 approved,investigational agonist
pramipexole dopamine d4 receptor small molecule NA drugbank , DGIDB Secondary Parkinson Disease[MeSHID:D010302]
Restless Legs Syndrome[MeSHID:D012148]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Parkinson Disease[MeSHID:D010300]		 2.32 approved,investigational agonist
pramipexole 5-hydroxytryptamine receptor 1a small molecule NA drugbank Secondary Parkinson Disease[MeSHID:D010302]
Restless Legs Syndrome[MeSHID:D012148]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Parkinson Disease[MeSHID:D010300]		 NA approved,investigational agonist
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