Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
plecanatide guanylate cyclase soluble subunit alpha-2 small molecule NA drugbank Defecation[MeSHID:D003672]
Intestinal Secretions[MeSHID:D007419]
Body Fluids[MeSHID:D001826]
Upper Gastrointestinal Tract[MeSHID:D041742]
Irritable Bowel Syndrome[MeSHID:D043183]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Crohn Disease[MeSHID:D003424]
Constipation[MeSHID:D003248]		 NA approved,investigational agonist
plecanatide guanylyl cyclase c NA Successful target TTD , DGIDB Defecation[MeSHID:D003672]
Intestinal Secretions[MeSHID:D007419]
Body Fluids[MeSHID:D001826]
Upper Gastrointestinal Tract[MeSHID:D041742]
Irritable Bowel Syndrome[MeSHID:D043183]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Crohn Disease[MeSHID:D003424]
Constipation[MeSHID:D003248]		 63.65 approved agonist
plecanatide guanylyl cyclase c NA Successful target TTD , DGIDB Defecation[MeSHID:D003672]
Intestinal Secretions[MeSHID:D007419]
Body Fluids[MeSHID:D001826]
Upper Gastrointestinal Tract[MeSHID:D041742]
Irritable Bowel Syndrome[MeSHID:D043183]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Crohn Disease[MeSHID:D003424]
Constipation[MeSHID:D003248]		 63.65 approved unknown
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