Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
pilocarpine muscarinic acetylcholine receptor m1 small molecule NA drugbank , DGIDB Radiation[MeSHID:D011827]
Presbyopia[MeSHID:D011305]
Xerostomia[MeSHID:D014987]
Syndrome[MeSHID:D013577]
Electromagnetic Radiation[MeSHID:D060733]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Ocular Hypertension[MeSHID:D009798]
Glaucoma[MeSHID:D005901]		 0.37 approved,investigational agonist
pilocarpine muscarinic acetylcholine receptor m2 small molecule NA drugbank , DGIDB Radiation[MeSHID:D011827]
Presbyopia[MeSHID:D011305]
Xerostomia[MeSHID:D014987]
Syndrome[MeSHID:D013577]
Electromagnetic Radiation[MeSHID:D060733]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Ocular Hypertension[MeSHID:D009798]
Glaucoma[MeSHID:D005901]		 0.33 approved,investigational agonist
pilocarpine muscarinic acetylcholine receptor m3 small molecule NA drugbank , DGIDB Radiation[MeSHID:D011827]
Presbyopia[MeSHID:D011305]
Xerostomia[MeSHID:D014987]
Syndrome[MeSHID:D013577]
Electromagnetic Radiation[MeSHID:D060733]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Ocular Hypertension[MeSHID:D009798]
Glaucoma[MeSHID:D005901]		 0.23 approved,investigational agonist
pilocarpine muscarinic acetylcholine receptor m4 small molecule NA drugbank , DGIDB Radiation[MeSHID:D011827]
Presbyopia[MeSHID:D011305]
Xerostomia[MeSHID:D014987]
Syndrome[MeSHID:D013577]
Electromagnetic Radiation[MeSHID:D060733]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Ocular Hypertension[MeSHID:D009798]
Glaucoma[MeSHID:D005901]		 0.15 approved,investigational partial agonist,agonist
pilocarpine muscarinic acetylcholine receptor m5 NA Successful target TTD , DGIDB Radiation[MeSHID:D011827]
Presbyopia[MeSHID:D011305]
Xerostomia[MeSHID:D014987]
Syndrome[MeSHID:D013577]
Electromagnetic Radiation[MeSHID:D060733]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Ocular Hypertension[MeSHID:D009798]
Glaucoma[MeSHID:D005901]		 0.14 approved agonist
pilocarpine muscarinic acetylcholine receptor m5 NA Successful target TTD , DGIDB Radiation[MeSHID:D011827]
Presbyopia[MeSHID:D011305]
Xerostomia[MeSHID:D014987]
Syndrome[MeSHID:D013577]
Electromagnetic Radiation[MeSHID:D060733]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Ocular Hypertension[MeSHID:D009798]
Glaucoma[MeSHID:D005901]		 0.14 approved unknown
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