Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
pentoxifylline adenosine receptor a1 small molecule NA drugbank , DGIDB Blood Vessel[MeSHID:D001808]
Operative Surgical Procedures[MeSHID:D013514]
Limb structure[MeSHID:D005121]
Intermittent Claudication[MeSHID:D007383]
Arterial Occlusive Diseases[MeSHID:D001157]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.08 approved,investigational unknown
pentoxifylline adenosine receptor a2a small molecule NA drugbank , DGIDB Blood Vessel[MeSHID:D001808]
Operative Surgical Procedures[MeSHID:D013514]
Limb structure[MeSHID:D005121]
Intermittent Claudication[MeSHID:D007383]
Arterial Occlusive Diseases[MeSHID:D001157]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.07 approved,investigational agonist,antagonist
pentoxifylline 5'-nucleotidase small molecule NA drugbank Blood Vessel[MeSHID:D001808]
Operative Surgical Procedures[MeSHID:D013514]
Limb structure[MeSHID:D005121]
Intermittent Claudication[MeSHID:D007383]
Arterial Occlusive Diseases[MeSHID:D001157]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,investigational inhibitor
pentoxifylline tumor necrosis factor NA Successful target TTD , DGIDB Blood Vessel[MeSHID:D001808]
Operative Surgical Procedures[MeSHID:D013514]
Limb structure[MeSHID:D005121]
Intermittent Claudication[MeSHID:D007383]
Arterial Occlusive Diseases[MeSHID:D001157]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.03 approved unknown
pentoxifylline phosphodiesterase enzymes small molecule NA drugbank Blood Vessel[MeSHID:D001808]
Operative Surgical Procedures[MeSHID:D013514]
Limb structure[MeSHID:D005121]
Intermittent Claudication[MeSHID:D007383]
Arterial Occlusive Diseases[MeSHID:D001157]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,investigational inhibitor
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