Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
pexidartinib macrophage colony-stimulating factor 1 receptor small molecule Successful target TTD , drugbank , DGIDB Giant Cell Tumors[MeSHID:D005870]
Operative Surgical Procedures[MeSHID:D013514]
Testicular Germ Cell Tumor[MeSHID:C563236]
Pigmented villonodular synovitis[MeSHID:D013586]
Neurofibromatosis 1[MeSHID:D009456]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.96 approved,investigational inhibitor
pexidartinib fms-like tyrosine kinase 3 NA Successful target TTD , DGIDB Giant Cell Tumors[MeSHID:D005870]
Operative Surgical Procedures[MeSHID:D013514]
Testicular Germ Cell Tumor[MeSHID:C563236]
Pigmented villonodular synovitis[MeSHID:D013586]
Neurofibromatosis 1[MeSHID:D009456]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.54 approved inhibitor
pexidartinib fms-like tyrosine kinase 3 NA Successful target TTD , DGIDB Giant Cell Tumors[MeSHID:D005870]
Operative Surgical Procedures[MeSHID:D013514]
Testicular Germ Cell Tumor[MeSHID:C563236]
Pigmented villonodular synovitis[MeSHID:D013586]
Neurofibromatosis 1[MeSHID:D009456]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.54 approved unknown
pexidartinib receptor-type tyrosine-protein kinase flt3 small molecule NA drugbank , DGIDB Giant Cell Tumors[MeSHID:D005870]
Operative Surgical Procedures[MeSHID:D013514]
Testicular Germ Cell Tumor[MeSHID:C563236]
Pigmented villonodular synovitis[MeSHID:D013586]
Neurofibromatosis 1[MeSHID:D009456]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.54 approved,investigational inhibitor
pexidartinib tyrosine-protein kinase kit NA Successful target TTD , DGIDB Giant Cell Tumors[MeSHID:D005870]
Operative Surgical Procedures[MeSHID:D013514]
Testicular Germ Cell Tumor[MeSHID:C563236]
Pigmented villonodular synovitis[MeSHID:D013586]
Neurofibromatosis 1[MeSHID:D009456]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.64 approved inhibitor
pexidartinib mast/stem cell growth factor receptor kit small molecule NA drugbank , DGIDB Giant Cell Tumors[MeSHID:D005870]
Operative Surgical Procedures[MeSHID:D013514]
Testicular Germ Cell Tumor[MeSHID:C563236]
Pigmented villonodular synovitis[MeSHID:D013586]
Neurofibromatosis 1[MeSHID:D009456]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.64 approved,investigational inhibitor
pexidartinib platelet-derived growth factor receptor beta small molecule NA drugbank Giant Cell Tumors[MeSHID:D005870]
Operative Surgical Procedures[MeSHID:D013514]
Testicular Germ Cell Tumor[MeSHID:C563236]
Pigmented villonodular synovitis[MeSHID:D013586]
Neurofibromatosis 1[MeSHID:D009456]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,investigational inhibitor
click here to return to the previous page