| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| perifosine | rac-alpha serine/threonine-protein kinase | small molecule | NA | drugbank , DGIDB | Neoplasms[MeSHID:D009369] Malignant neoplasm of lung[MeSHID:D008175] leukemia[MeSHID:D007938] Malignant neoplasm of brain[MeSHID:D001932] Multiple Myeloma[MeSHID:D009101] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant Neoplasms[MeSHID:D009369] |
1.05 | investigational | unknown |
| perifosine | rac-alpha serine/threonine-protein kinase | small molecule | NA | drugbank , DGIDB | Neoplasms[MeSHID:D009369] Malignant neoplasm of lung[MeSHID:D008175] leukemia[MeSHID:D007938] Malignant neoplasm of brain[MeSHID:D001932] Multiple Myeloma[MeSHID:D009101] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant Neoplasms[MeSHID:D009369] |
1.05 | investigational | inhibitor |
| perifosine | mitogen-activated protein kinase 1 | small molecule | NA | drugbank | Neoplasms[MeSHID:D009369] Malignant neoplasm of lung[MeSHID:D008175] leukemia[MeSHID:D007938] Malignant neoplasm of brain[MeSHID:D001932] Multiple Myeloma[MeSHID:D009101] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant Neoplasms[MeSHID:D009369] |
NA | investigational | unknown |
| perifosine | pi3-kinase gamma | NA | Successful target | TTD , DGIDB | Neoplasms[MeSHID:D009369] Malignant neoplasm of lung[MeSHID:D008175] leukemia[MeSHID:D007938] Malignant neoplasm of brain[MeSHID:D001932] Multiple Myeloma[MeSHID:D009101] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant Neoplasms[MeSHID:D009369] |
0.13 | phase 1 | unknown |
| perifosine | protein kinase c alpha type | small molecule | NA | drugbank | Neoplasms[MeSHID:D009369] Malignant neoplasm of lung[MeSHID:D008175] leukemia[MeSHID:D007938] Malignant neoplasm of brain[MeSHID:D001932] Multiple Myeloma[MeSHID:D009101] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant Neoplasms[MeSHID:D009369] |
NA | investigational | unknown |
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