Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
penbutolol adrenergic receptor beta-1 NA Successful target TTD , DGIDB Hypertensive disease[MeSHID:D006973]
Shock
Cardiogenic[MeSHID:D012770]
Atrioventricular Block[MeSHID:D054537]
Neoplasm Metastasis[MeSHID:D009362]
Asthma[MeSHID:D001249]
Bradycardia[MeSHID:D001919]
Hypersensitivity[MeSHID:D006967]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
2.42 approved unknown
penbutolol beta-1 adrenergic receptor small molecule NA drugbank , DGIDB Hypertensive disease[MeSHID:D006973]
Shock
Cardiogenic[MeSHID:D012770]
Atrioventricular Block[MeSHID:D054537]
Neoplasm Metastasis[MeSHID:D009362]
Asthma[MeSHID:D001249]
Bradycardia[MeSHID:D001919]
Hypersensitivity[MeSHID:D006967]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
2.42 approved,investigational antagonist,partial agonist
penbutolol beta-2 adrenergic receptor small molecule NA drugbank , DGIDB Hypertensive disease[MeSHID:D006973]
Shock
Cardiogenic[MeSHID:D012770]
Atrioventricular Block[MeSHID:D054537]
Neoplasm Metastasis[MeSHID:D009362]
Asthma[MeSHID:D001249]
Bradycardia[MeSHID:D001919]
Hypersensitivity[MeSHID:D006967]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
1.84 approved,investigational antagonist,partial agonist
penbutolol 5-hydroxytryptamine receptor 1a small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Shock
Cardiogenic[MeSHID:D012770]
Atrioventricular Block[MeSHID:D054537]
Neoplasm Metastasis[MeSHID:D009362]
Asthma[MeSHID:D001249]
Bradycardia[MeSHID:D001919]
Hypersensitivity[MeSHID:D006967]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
NA approved,investigational antagonist
penbutolol 5-hydroxytryptamine receptor 1b small molecule NA drugbank Hypertensive disease[MeSHID:D006973]
Shock
Cardiogenic[MeSHID:D012770]
Atrioventricular Block[MeSHID:D054537]
Neoplasm Metastasis[MeSHID:D009362]
Asthma[MeSHID:D001249]
Bradycardia[MeSHID:D001919]
Hypersensitivity[MeSHID:D006967]
pathologic fistula[MeSHID:D005402]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
NA approved,investigational antagonist
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