Drug-Target Information | ||||||||
---|---|---|---|---|---|---|---|---|
Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
penbutolol | adrenergic receptor beta-1 | NA | Successful target | TTD , DGIDB | Hypertensive disease[MeSHID:D006973] Shock Cardiogenic[MeSHID:D012770] Atrioventricular Block[MeSHID:D054537] Neoplasm Metastasis[MeSHID:D009362] Asthma[MeSHID:D001249] Bradycardia[MeSHID:D001919] Hypersensitivity[MeSHID:D006967] pathologic fistula[MeSHID:D005402] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
2.42 | approved | unknown |
penbutolol | beta-1 adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Shock Cardiogenic[MeSHID:D012770] Atrioventricular Block[MeSHID:D054537] Neoplasm Metastasis[MeSHID:D009362] Asthma[MeSHID:D001249] Bradycardia[MeSHID:D001919] Hypersensitivity[MeSHID:D006967] pathologic fistula[MeSHID:D005402] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
2.42 | approved,investigational | antagonist,partial agonist |
penbutolol | beta-2 adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypertensive disease[MeSHID:D006973] Shock Cardiogenic[MeSHID:D012770] Atrioventricular Block[MeSHID:D054537] Neoplasm Metastasis[MeSHID:D009362] Asthma[MeSHID:D001249] Bradycardia[MeSHID:D001919] Hypersensitivity[MeSHID:D006967] pathologic fistula[MeSHID:D005402] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.84 | approved,investigational | antagonist,partial agonist |
penbutolol | 5-hydroxytryptamine receptor 1a | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Shock Cardiogenic[MeSHID:D012770] Atrioventricular Block[MeSHID:D054537] Neoplasm Metastasis[MeSHID:D009362] Asthma[MeSHID:D001249] Bradycardia[MeSHID:D001919] Hypersensitivity[MeSHID:D006967] pathologic fistula[MeSHID:D005402] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist |
penbutolol | 5-hydroxytryptamine receptor 1b | small molecule | NA | drugbank | Hypertensive disease[MeSHID:D006973] Shock Cardiogenic[MeSHID:D012770] Atrioventricular Block[MeSHID:D054537] Neoplasm Metastasis[MeSHID:D009362] Asthma[MeSHID:D001249] Bradycardia[MeSHID:D001919] Hypersensitivity[MeSHID:D006967] pathologic fistula[MeSHID:D005402] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist |
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