| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| paramethadione | voltage-gated calcium channel alpha cav3.1 | NA | Successful target | TTD , DGIDB | Absence Epilepsy[MeSHID:D004832] Seizures[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] Fetal trimethadione syndrome[MeSHID:C537798] |
2.12 | approved | unknown |
| paramethadione | voltage-gated calcium channel alpha cav3.1 | NA | Successful target | TTD , DGIDB | Absence Epilepsy[MeSHID:D004832] Seizures[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] Fetal trimethadione syndrome[MeSHID:C537798] |
2.12 | approved | blocker |
| paramethadione | voltage-dependent t-type calcium channel subunit alpha-1i | small molecule | NA | drugbank , DGIDB | Absence Epilepsy[MeSHID:D004832] Seizures[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] Fetal trimethadione syndrome[MeSHID:C537798] |
6.37 | approved | inhibitor |
| paramethadione | voltage-dependent t-type calcium channel subunit alpha-1i | small molecule | NA | drugbank , DGIDB | Absence Epilepsy[MeSHID:D004832] Seizures[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Epilepsy[MeSHID:D004827] Fetal trimethadione syndrome[MeSHID:C537798] |
6.37 | approved | inhibitor,blocker |
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