| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| pamidronic acid | caspase-3 | small molecule | NA | drugbank | Lytic lesion[MeSHID:D010014] Breast[MeSHID:D001940] Neoplasm Metastasis[MeSHID:D009362] Osteitis Deformans[MeSHID:D010001] Malignant Bone Neoplasm[MeSHID:D001859] Malignant neoplasm of breast[MeSHID:D001943] Humoral hypercalcemia of malignancy (disorder)[MeSHID:C562390] Bone Tissue[MeSHID:D001842] Multiple Myeloma[MeSHID:D009101] |
NA | approved | activator |
| pamidronic acid | caspase-9 | small molecule | NA | drugbank | Lytic lesion[MeSHID:D010014] Breast[MeSHID:D001940] Neoplasm Metastasis[MeSHID:D009362] Osteitis Deformans[MeSHID:D010001] Malignant Bone Neoplasm[MeSHID:D001859] Malignant neoplasm of breast[MeSHID:D001943] Humoral hypercalcemia of malignancy (disorder)[MeSHID:C562390] Bone Tissue[MeSHID:D001842] Multiple Myeloma[MeSHID:D009101] |
NA | approved | activator |
| pamidronic acid | farnesyl pyrophosphate synthase | small molecule | NA | drugbank , DGIDB | Lytic lesion[MeSHID:D010014] Breast[MeSHID:D001940] Neoplasm Metastasis[MeSHID:D009362] Osteitis Deformans[MeSHID:D010001] Malignant Bone Neoplasm[MeSHID:D001859] Malignant neoplasm of breast[MeSHID:D001943] Humoral hypercalcemia of malignancy (disorder)[MeSHID:C562390] Bone Tissue[MeSHID:D001842] Multiple Myeloma[MeSHID:D009101] |
NA | approved | inhibitor |
| pamidronic acid | geranylgeranyl pyrophosphate synthase | small molecule | NA | drugbank | Lytic lesion[MeSHID:D010014] Breast[MeSHID:D001940] Neoplasm Metastasis[MeSHID:D009362] Osteitis Deformans[MeSHID:D010001] Malignant Bone Neoplasm[MeSHID:D001859] Malignant neoplasm of breast[MeSHID:D001943] Humoral hypercalcemia of malignancy (disorder)[MeSHID:C562390] Bone Tissue[MeSHID:D001842] Multiple Myeloma[MeSHID:D009101] |
NA | approved | inhibitor |
| pamidronic acid | hydroxylapatite | small molecule | NA | drugbank | Lytic lesion[MeSHID:D010014] Breast[MeSHID:D001940] Neoplasm Metastasis[MeSHID:D009362] Osteitis Deformans[MeSHID:D010001] Malignant Bone Neoplasm[MeSHID:D001859] Malignant neoplasm of breast[MeSHID:D001943] Humoral hypercalcemia of malignancy (disorder)[MeSHID:C562390] Bone Tissue[MeSHID:D001842] Multiple Myeloma[MeSHID:D009101] |
NA | approved | antagonist |
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