Drug-Target Information | ||||||||
---|---|---|---|---|---|---|---|---|
Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
olanzapine | alpha-1a adrenergic receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.03 | approved,investigational | antagonist |
olanzapine | alpha-1b adrenergic receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.07 | approved,investigational | antagonist |
olanzapine | beta adrenergic receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
olanzapine | beta adrenergic receptor | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
olanzapine | beta adrenergic receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | approved,investigational | inhibitor |
olanzapine | muscarinic acetylcholine receptor m1 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | approved,investigational | antagonist |
olanzapine | muscarinic acetylcholine receptor m2 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.06 | approved,investigational | antagonist |
olanzapine | muscarinic acetylcholine receptor m3 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | approved,investigational | antagonist |
olanzapine | muscarinic acetylcholine receptor m4 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.08 | approved,investigational | antagonist |
olanzapine | d(1) dopamine receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | approved,investigational | antagonist |
olanzapine | dopamine d1 receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | approved,investigational | antagonist |
olanzapine | dopamine d2 receptor | small molecule | Successful target | TTD , drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.22 | approved,investigational | antagonist |
olanzapine | dopamine d3 receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.09 | approved,investigational | antagonist |
olanzapine | dopamine d4 receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.09 | approved,investigational | antagonist |
olanzapine | d(1) dopamine receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.12 | approved,investigational | antagonist |
olanzapine | dopamine d5 receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.12 | approved,investigational | antagonist |
olanzapine | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
olanzapine | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
olanzapine | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
olanzapine | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
olanzapine | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
olanzapine | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
olanzapine | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
olanzapine | histamine h1 receptor | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.06 | approved,investigational | antagonist |
olanzapine | 5-hydroxytryptamine receptor 1 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | approved,investigational | inhibitor |
olanzapine | 5-hydroxytryptamine receptor 1 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | approved,investigational | inhibitor,agonist |
olanzapine | 5-hydroxytryptamine receptor 1 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.04 | approved,investigational | inhibitor |
olanzapine | 5-hydroxytryptamine receptor 1 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.04 | approved,investigational | inhibitor,agonist |
olanzapine | 5-hydroxytryptamine receptor 1 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | approved,investigational | inhibitor |
olanzapine | 5-hydroxytryptamine receptor 1 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | approved,investigational | inhibitor,agonist |
olanzapine | 5-hydroxytryptamine receptor 1 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.09 | approved,investigational | inhibitor,agonist |
olanzapine | 5-hydroxytryptamine receptor 1 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.09 | approved,investigational | inhibitor |
olanzapine | 5-hydroxytryptamine receptor 1 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.03 | approved,investigational | inhibitor,agonist |
olanzapine | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.13 | approved,investigational | antagonist |
olanzapine | 5-hydroxytryptamine receptor 2c | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.26 | approved,investigational | antagonist |
olanzapine | 5-hydroxytryptamine receptor 3a | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.06 | approved,investigational | antagonist |
olanzapine | 5-hydroxytryptamine receptor 6 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Schizophrenia[MeSHID:D012559] Abnormal behavior[MeSHID:D000066553] Depressive disorder[MeSHID:D003866] Bipolar Disorder[MeSHID:D001714] Maintenance[MeSHID:D008283] Ability[MeSHID:D001076] Hallucinations[MeSHID:D006212] Delusions[MeSHID:D003702] Psychomotor Agitation[MeSHID:D011595] Affect (mental function)[MeSHID:D000339] Depressive Disorder Treatment-Resistant[MeSHID:D061218] Mental Depression[MeSHID:D003863] Thinking function[MeSHID:D013850] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.09 | approved,investigational | antagonist |
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