Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
obeticholic acid farnesoid x-activated receptor NA Successful target TTD , DGIDB Liver[MeSHID:D008099]
Bile fluid[MeSHID:D001646]
Primary biliary cirrhosis[MeSHID:D008105]
Fibrosis[MeSHID:D005355]
Nonalcoholic Steatohepatitis[MeSHID:D065626]
Cholangitis[MeSHID:D002761]
Sleeplessness[MeSHID:D007319]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved agonist
obeticholic acid bile acid receptor small molecule NA drugbank , DGIDB Liver[MeSHID:D008099]
Bile fluid[MeSHID:D001646]
Primary biliary cirrhosis[MeSHID:D008105]
Fibrosis[MeSHID:D005355]
Nonalcoholic Steatohepatitis[MeSHID:D065626]
Cholangitis[MeSHID:D002761]
Sleeplessness[MeSHID:D007319]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved agonist
obeticholic acid farnesoid x-activated receptor NA Successful target TTD , DGIDB Liver[MeSHID:D008099]
Bile fluid[MeSHID:D001646]
Primary biliary cirrhosis[MeSHID:D008105]
Fibrosis[MeSHID:D005355]
Nonalcoholic Steatohepatitis[MeSHID:D065626]
Cholangitis[MeSHID:D002761]
Sleeplessness[MeSHID:D007319]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 4.68 approved unknown
obeticholic acid farnesoid x-activated receptor NA Successful target TTD , DGIDB Liver[MeSHID:D008099]
Bile fluid[MeSHID:D001646]
Primary biliary cirrhosis[MeSHID:D008105]
Fibrosis[MeSHID:D005355]
Nonalcoholic Steatohepatitis[MeSHID:D065626]
Cholangitis[MeSHID:D002761]
Sleeplessness[MeSHID:D007319]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 4.68 approved agonist
obeticholic acid bile acid receptor small molecule NA drugbank , DGIDB Liver[MeSHID:D008099]
Bile fluid[MeSHID:D001646]
Primary biliary cirrhosis[MeSHID:D008105]
Fibrosis[MeSHID:D005355]
Nonalcoholic Steatohepatitis[MeSHID:D065626]
Cholangitis[MeSHID:D002761]
Sleeplessness[MeSHID:D007319]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 4.68 approved agonist
obeticholic acid farnesoid x-activated receptor NA Successful target TTD , DGIDB Liver[MeSHID:D008099]
Bile fluid[MeSHID:D001646]
Primary biliary cirrhosis[MeSHID:D008105]
Fibrosis[MeSHID:D005355]
Nonalcoholic Steatohepatitis[MeSHID:D065626]
Cholangitis[MeSHID:D002761]
Sleeplessness[MeSHID:D007319]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved unknown
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