| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| norepinephrine | alpha-1a adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypotension[MeSHID:D007022] Neurogenesis[MeSHID:D055495] Continuance of life[MeSHID:D013534] Shock[MeSHID:D012769] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] |
0.2 | approved | agonist |
| norepinephrine | alpha-1b adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypotension[MeSHID:D007022] Neurogenesis[MeSHID:D055495] Continuance of life[MeSHID:D013534] Shock[MeSHID:D012769] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] |
0.35 | approved | agonist |
| norepinephrine | alpha-1d adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypotension[MeSHID:D007022] Neurogenesis[MeSHID:D055495] Continuance of life[MeSHID:D013534] Shock[MeSHID:D012769] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] |
0.59 | approved | agonist |
| norepinephrine | alpha-2a adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypotension[MeSHID:D007022] Neurogenesis[MeSHID:D055495] Continuance of life[MeSHID:D013534] Shock[MeSHID:D012769] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] |
0.42 | approved | agonist |
| norepinephrine | alpha-2b adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypotension[MeSHID:D007022] Neurogenesis[MeSHID:D055495] Continuance of life[MeSHID:D013534] Shock[MeSHID:D012769] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] |
0.4 | approved | agonist |
| norepinephrine | alpha-2c adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypotension[MeSHID:D007022] Neurogenesis[MeSHID:D055495] Continuance of life[MeSHID:D013534] Shock[MeSHID:D012769] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] |
0.33 | approved | agonist |
| norepinephrine | adrenergic receptor beta-1 | NA | Successful target | TTD , DGIDB | Hypotension[MeSHID:D007022] Neurogenesis[MeSHID:D055495] Continuance of life[MeSHID:D013534] Shock[MeSHID:D012769] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] |
0.27 | approved | unknown |
| norepinephrine | beta-1 adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypotension[MeSHID:D007022] Neurogenesis[MeSHID:D055495] Continuance of life[MeSHID:D013534] Shock[MeSHID:D012769] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] |
0.27 | approved | agonist |
| norepinephrine | beta-2 adrenergic receptor | small molecule | NA | drugbank , DGIDB | Hypotension[MeSHID:D007022] Neurogenesis[MeSHID:D055495] Continuance of life[MeSHID:D013534] Shock[MeSHID:D012769] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] |
0.2 | approved | agonist |
| norepinephrine | beta-3 adrenergic receptor | small molecule | NA | drugbank | Hypotension[MeSHID:D007022] Neurogenesis[MeSHID:D055495] Continuance of life[MeSHID:D013534] Shock[MeSHID:D012769] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] |
NA | approved | agonist |
| norepinephrine | phenylalanine-4-hydroxylase | small molecule | NA | drugbank | Hypotension[MeSHID:D007022] Neurogenesis[MeSHID:D055495] Continuance of life[MeSHID:D013534] Shock[MeSHID:D012769] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] |
NA | approved | inhibitor |
| norepinephrine | chromaffin granule amine transporter | small molecule | NA | drugbank | Hypotension[MeSHID:D007022] Neurogenesis[MeSHID:D055495] Continuance of life[MeSHID:D013534] Shock[MeSHID:D012769] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] |
NA | approved | binder |
| norepinephrine | synaptic vesicular amine transporter | small molecule | NA | drugbank | Hypotension[MeSHID:D007022] Neurogenesis[MeSHID:D055495] Continuance of life[MeSHID:D013534] Shock[MeSHID:D012769] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] |
NA | approved | binder |
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