| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| nicotine | choline o-acetyltransferase | small molecule | NA | drugbank | Cessation of smoking[MeSHID:D016540] Withdrawal Symptoms[MeSHID:D013375] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Nicotine Dependence[MeSHID:D014029] |
NA | approved | inhibitor |
| nicotine | neuronal acetylcholine receptor subunit alpha-10 | small molecule | NA | drugbank , DGIDB | Cessation of smoking[MeSHID:D016540] Withdrawal Symptoms[MeSHID:D013375] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Nicotine Dependence[MeSHID:D014029] |
1.52 | approved | agonist,antagonist |
| nicotine | neuronal acetylcholine receptor subunit alpha-10 | small molecule | NA | drugbank , DGIDB | Cessation of smoking[MeSHID:D016540] Withdrawal Symptoms[MeSHID:D013375] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Nicotine Dependence[MeSHID:D014029] |
1.52 | approved | agonist |
| nicotine | neuronal acetylcholine receptor subunit alpha-2 | small molecule | NA | drugbank , DGIDB | Cessation of smoking[MeSHID:D016540] Withdrawal Symptoms[MeSHID:D013375] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Nicotine Dependence[MeSHID:D014029] |
0.45 | approved | agonist |
| nicotine | neuronal acetylcholine receptor subunit alpha-3 | small molecule | NA | drugbank , DGIDB | Cessation of smoking[MeSHID:D016540] Withdrawal Symptoms[MeSHID:D013375] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Nicotine Dependence[MeSHID:D014029] |
0.58 | approved | agonist |
| nicotine | neuronal acetylcholine receptor subunit alpha-4 | small molecule | NA | drugbank , DGIDB | Cessation of smoking[MeSHID:D016540] Withdrawal Symptoms[MeSHID:D013375] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Nicotine Dependence[MeSHID:D014029] |
0.7 | approved | agonist |
| nicotine | neuronal acetylcholine receptor subunit alpha-5 | small molecule | NA | drugbank | Cessation of smoking[MeSHID:D016540] Withdrawal Symptoms[MeSHID:D013375] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Nicotine Dependence[MeSHID:D014029] |
NA | approved | agonist |
| nicotine | neuronal acetylcholine receptor subunit alpha-6 | small molecule | NA | drugbank | Cessation of smoking[MeSHID:D016540] Withdrawal Symptoms[MeSHID:D013375] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Nicotine Dependence[MeSHID:D014029] |
NA | approved | agonist |
| nicotine | neuronal acetylcholine receptor subunit alpha-7 | small molecule | NA | drugbank , DGIDB | Cessation of smoking[MeSHID:D016540] Withdrawal Symptoms[MeSHID:D013375] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Nicotine Dependence[MeSHID:D014029] |
0.3 | approved | agonist |
| nicotine | neuronal acetylcholine receptor subunit alpha-9 | small molecule | NA | drugbank , DGIDB | Cessation of smoking[MeSHID:D016540] Withdrawal Symptoms[MeSHID:D013375] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Nicotine Dependence[MeSHID:D014029] |
2.27 | approved | agonist,antagonist |
| nicotine | neuronal acetylcholine receptor subunit alpha-9 | small molecule | NA | drugbank , DGIDB | Cessation of smoking[MeSHID:D016540] Withdrawal Symptoms[MeSHID:D013375] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Nicotine Dependence[MeSHID:D014029] |
2.27 | approved | agonist |
| nicotine | neuronal acetylcholine receptor subunit beta-2 | small molecule | NA | drugbank , DGIDB | Cessation of smoking[MeSHID:D016540] Withdrawal Symptoms[MeSHID:D013375] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Nicotine Dependence[MeSHID:D014029] |
1.06 | approved | agonist |
| nicotine | neuronal acetylcholine receptor subunit beta-3 | small molecule | NA | drugbank | Cessation of smoking[MeSHID:D016540] Withdrawal Symptoms[MeSHID:D013375] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Nicotine Dependence[MeSHID:D014029] |
NA | approved | agonist |
| nicotine | neuronal acetylcholine receptor subunit beta-4 | small molecule | NA | drugbank , DGIDB | Cessation of smoking[MeSHID:D016540] Withdrawal Symptoms[MeSHID:D013375] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Nicotine Dependence[MeSHID:D014029] |
0.6 | approved | agonist |
| nicotine | cytochrome p450 19a1 | small molecule | NA | drugbank | Cessation of smoking[MeSHID:D016540] Withdrawal Symptoms[MeSHID:D013375] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Nicotine Dependence[MeSHID:D014029] |
NA | approved | inhibitor |
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