Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
netarsudil rho-associated protein kinase 1 small molecule Successful target TTD , drugbank , DGIDB Glaucoma
Open-Angle[MeSHID:D005902]
Ocular Hypertension[MeSHID:D009798]
Ocular Hypotension[MeSHID:D015814]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Glaucoma[MeSHID:D005901]		 2.12 approved inhibitor
netarsudil rho-associated protein kinase 2 small molecule NA drugbank , DGIDB Glaucoma
Open-Angle[MeSHID:D005902]
Ocular Hypertension[MeSHID:D009798]
Ocular Hypotension[MeSHID:D015814]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Glaucoma[MeSHID:D005901]		 0.91 approved inhibitor
netarsudil norepinephrine transporter NA Successful target TTD Glaucoma
Open-Angle[MeSHID:D005902]
Ocular Hypertension[MeSHID:D009798]
Ocular Hypotension[MeSHID:D015814]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Glaucoma[MeSHID:D005901]		 NA approved unknown
netarsudil sodium-dependent noradrenaline transporter small molecule NA drugbank Glaucoma
Open-Angle[MeSHID:D005902]
Ocular Hypertension[MeSHID:D009798]
Ocular Hypotension[MeSHID:D015814]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Glaucoma[MeSHID:D005901]		 NA approved inhibitor
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