| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| nefazodone | alpha-1a adrenergic receptor | small molecule | NA | drugbank , DGIDB | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] |
0.21 | approved,withdrawn | antagonist |
| nefazodone | alpha-1b adrenergic receptor | small molecule | NA | drugbank , DGIDB | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] |
0.37 | approved,withdrawn | unknown |
| nefazodone | alpha-2a adrenergic receptor | small molecule | NA | drugbank | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] |
NA | approved,withdrawn | antagonist |
| nefazodone | 5-hydroxytryptamine receptor 1a | small molecule | NA | drugbank | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] |
NA | approved,withdrawn | antagonist |
| nefazodone | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank , DGIDB | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] |
0.44 | approved,withdrawn | antagonist |
| nefazodone | 5-hydroxytryptamine receptor 2c | small molecule | NA | drugbank , DGIDB | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] |
0.18 | approved,withdrawn | antagonist |
| nefazodone | 5-ht 2c receptor | NA | Successful target | TTD , DGIDB | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] |
0.18 | approved | unknown |
| nefazodone | potassium voltage-gated channel subfamily h member 2 | small molecule | NA | drugbank | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] |
NA | approved,withdrawn | antagonist |
| nefazodone | sodium-dependent noradrenaline transporter | small molecule | NA | drugbank , DGIDB | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] |
0.94 | approved,withdrawn | inhibitor |
| nefazodone | sodium-dependent dopamine transporter | small molecule | NA | drugbank | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] |
NA | approved,withdrawn | inhibitor |
| nefazodone | sodium-dependent serotonin transporter | small molecule | NA | drugbank , DGIDB | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Major Depressive Disorder[MeSHID:D003865] |
0.78 | approved,withdrawn | inhibitor |
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