| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| naloxone | liver carboxylesterase 1 | small molecule | NA | drugbank | Pruritus[MeSHID:D011537] Depressive disorder[MeSHID:D003866] Opiate Addiction[MeSHID:D009293] Diagnosis[MeSHID:D003933] Drug Overdose[MeSHID:D062787] Off-Label Use[MeSHID:D056687] Mental Depression[MeSHID:D003863] Pain[MeSHID:D010146] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Respiratory Depression[MeSHID:D012131] |
NA | approved,vet_approved | binder |
| naloxone | cyclic amp-responsive element-binding protein 1 | small molecule | NA | drugbank | Pruritus[MeSHID:D011537] Depressive disorder[MeSHID:D003866] Opiate Addiction[MeSHID:D009293] Diagnosis[MeSHID:D003933] Drug Overdose[MeSHID:D062787] Off-Label Use[MeSHID:D056687] Mental Depression[MeSHID:D003863] Pain[MeSHID:D010146] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Respiratory Depression[MeSHID:D012131] |
NA | approved,vet_approved | unknown |
| naloxone | estrogen receptor alpha | small molecule | NA | drugbank | Pruritus[MeSHID:D011537] Depressive disorder[MeSHID:D003866] Opiate Addiction[MeSHID:D009293] Diagnosis[MeSHID:D003933] Drug Overdose[MeSHID:D062787] Off-Label Use[MeSHID:D056687] Mental Depression[MeSHID:D003863] Pain[MeSHID:D010146] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Respiratory Depression[MeSHID:D012131] |
NA | approved,vet_approved | antagonist, |
| naloxone | delta-type opioid receptor | small molecule | NA | drugbank , DGIDB | Pruritus[MeSHID:D011537] Depressive disorder[MeSHID:D003866] Opiate Addiction[MeSHID:D009293] Diagnosis[MeSHID:D003933] Drug Overdose[MeSHID:D062787] Off-Label Use[MeSHID:D056687] Mental Depression[MeSHID:D003863] Pain[MeSHID:D010146] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Respiratory Depression[MeSHID:D012131] |
1.07 | approved,vet_approved | antagonist |
| naloxone | kappa-type opioid receptor | small molecule | NA | drugbank , DGIDB | Pruritus[MeSHID:D011537] Depressive disorder[MeSHID:D003866] Opiate Addiction[MeSHID:D009293] Diagnosis[MeSHID:D003933] Drug Overdose[MeSHID:D062787] Off-Label Use[MeSHID:D056687] Mental Depression[MeSHID:D003863] Pain[MeSHID:D010146] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Respiratory Depression[MeSHID:D012131] |
0.33 | approved,vet_approved | antagonist |
| naloxone | opioid receptor mu | NA | Successful target | TTD , DGIDB | Pruritus[MeSHID:D011537] Depressive disorder[MeSHID:D003866] Opiate Addiction[MeSHID:D009293] Diagnosis[MeSHID:D003933] Drug Overdose[MeSHID:D062787] Off-Label Use[MeSHID:D056687] Mental Depression[MeSHID:D003863] Pain[MeSHID:D010146] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Respiratory Depression[MeSHID:D012131] |
0.89 | approved | antagonist |
| naloxone | mu-type opioid receptor | small molecule | NA | drugbank , DGIDB | Pruritus[MeSHID:D011537] Depressive disorder[MeSHID:D003866] Opiate Addiction[MeSHID:D009293] Diagnosis[MeSHID:D003933] Drug Overdose[MeSHID:D062787] Off-Label Use[MeSHID:D056687] Mental Depression[MeSHID:D003863] Pain[MeSHID:D010146] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Respiratory Depression[MeSHID:D012131] |
0.89 | approved,vet_approved | antagonist |
| naloxone | opioid receptor mu | NA | Successful target | TTD , DGIDB | Pruritus[MeSHID:D011537] Depressive disorder[MeSHID:D003866] Opiate Addiction[MeSHID:D009293] Diagnosis[MeSHID:D003933] Drug Overdose[MeSHID:D062787] Off-Label Use[MeSHID:D056687] Mental Depression[MeSHID:D003863] Pain[MeSHID:D010146] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Respiratory Depression[MeSHID:D012131] |
0.89 | approved | unknown |
| naloxone | toll-like receptor 4 | small molecule | NA | drugbank | Pruritus[MeSHID:D011537] Depressive disorder[MeSHID:D003866] Opiate Addiction[MeSHID:D009293] Diagnosis[MeSHID:D003933] Drug Overdose[MeSHID:D062787] Off-Label Use[MeSHID:D056687] Mental Depression[MeSHID:D003863] Pain[MeSHID:D010146] Septic Shock[MeSHID:D012772] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Respiratory Depression[MeSHID:D012131] |
NA | approved,vet_approved | inhibitor |
| click here to return to the previous page | ||||||||