Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
nalmefene delta-type opioid receptor small molecule NA drugbank , DGIDB Disease Management[MeSHID:D019468]
Respiratory Depression[MeSHID:D012131]
Physical Examination[MeSHID:D010808]
Alcohol consumption[MeSHID:D000428]
Drug Overdose[MeSHID:D062787]
Alcoholic Intoxication
Chronic[MeSHID:D000437]
Drinking function[MeSHID:D004326]
Metabolic Detoxication
Drug[MeSHID:D008658]
Withdrawal Symptoms[MeSHID:D013375]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Opiate Addiction[MeSHID:D009293]		 1.31 approved,investigational,withdrawn antagonist,agonist
nalmefene delta-type opioid receptor small molecule NA drugbank , DGIDB Disease Management[MeSHID:D019468]
Respiratory Depression[MeSHID:D012131]
Physical Examination[MeSHID:D010808]
Alcohol consumption[MeSHID:D000428]
Drug Overdose[MeSHID:D062787]
Alcoholic Intoxication
Chronic[MeSHID:D000437]
Drinking function[MeSHID:D004326]
Metabolic Detoxication
Drug[MeSHID:D008658]
Withdrawal Symptoms[MeSHID:D013375]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Opiate Addiction[MeSHID:D009293]		 1.31 approved,investigational,withdrawn antagonist
nalmefene kappa-type opioid receptor small molecule NA drugbank , DGIDB Disease Management[MeSHID:D019468]
Respiratory Depression[MeSHID:D012131]
Physical Examination[MeSHID:D010808]
Alcohol consumption[MeSHID:D000428]
Drug Overdose[MeSHID:D062787]
Alcoholic Intoxication
Chronic[MeSHID:D000437]
Drinking function[MeSHID:D004326]
Metabolic Detoxication
Drug[MeSHID:D008658]
Withdrawal Symptoms[MeSHID:D013375]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Opiate Addiction[MeSHID:D009293]		 0.95 approved,investigational,withdrawn partial agonist,antagonist
nalmefene kappa-type opioid receptor small molecule NA drugbank , DGIDB Disease Management[MeSHID:D019468]
Respiratory Depression[MeSHID:D012131]
Physical Examination[MeSHID:D010808]
Alcohol consumption[MeSHID:D000428]
Drug Overdose[MeSHID:D062787]
Alcoholic Intoxication
Chronic[MeSHID:D000437]
Drinking function[MeSHID:D004326]
Metabolic Detoxication
Drug[MeSHID:D008658]
Withdrawal Symptoms[MeSHID:D013375]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Opiate Addiction[MeSHID:D009293]		 0.95 approved,investigational,withdrawn partial agonist
nalmefene mu-type opioid receptor small molecule NA drugbank , DGIDB Disease Management[MeSHID:D019468]
Respiratory Depression[MeSHID:D012131]
Physical Examination[MeSHID:D010808]
Alcohol consumption[MeSHID:D000428]
Drug Overdose[MeSHID:D062787]
Alcoholic Intoxication
Chronic[MeSHID:D000437]
Drinking function[MeSHID:D004326]
Metabolic Detoxication
Drug[MeSHID:D008658]
Withdrawal Symptoms[MeSHID:D013375]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Opiate Addiction[MeSHID:D009293]		 0.34 approved,investigational,withdrawn antagonist
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