| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| nafamostat | coagulation factor x | small molecule | NA | drugbank | Blood Vessel[MeSHID:D001808] Blood coagulation[MeSHID:D001777] Cell Respiration[MeSHID:D019069] Hemorrhage[MeSHID:D006470] Tissue membrane[MeSHID:D008566] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Middle East Respiratory Syndrome[MeSHID:D018352] Disease[MeSHID:D004194] |
NA | investigational | inhibitor |
| nafamostat | coagulation factor x | small molecule | NA | drugbank | Blood Vessel[MeSHID:D001808] Blood coagulation[MeSHID:D001777] Cell Respiration[MeSHID:D019069] Hemorrhage[MeSHID:D006470] Tissue membrane[MeSHID:D008566] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] Pancreatitis[MeSHID:D010195] |
NA | investigational | inhibitor |
| nafamostat | coagulation factor xii | small molecule | NA | drugbank | Blood Vessel[MeSHID:D001808] Blood coagulation[MeSHID:D001777] Cell Respiration[MeSHID:D019069] Hemorrhage[MeSHID:D006470] Tissue membrane[MeSHID:D008566] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Middle East Respiratory Syndrome[MeSHID:D018352] Disease[MeSHID:D004194] |
NA | investigational | inhibitor |
| nafamostat | coagulation factor xii | small molecule | NA | drugbank | Blood Vessel[MeSHID:D001808] Blood coagulation[MeSHID:D001777] Cell Respiration[MeSHID:D019069] Hemorrhage[MeSHID:D006470] Tissue membrane[MeSHID:D008566] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] Pancreatitis[MeSHID:D010195] |
NA | investigational | inhibitor |
| nafamostat | prothrombin | small molecule | NA | drugbank | Blood Vessel[MeSHID:D001808] Blood coagulation[MeSHID:D001777] Cell Respiration[MeSHID:D019069] Hemorrhage[MeSHID:D006470] Tissue membrane[MeSHID:D008566] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] Pancreatitis[MeSHID:D010195] |
NA | investigational | inhibitor |
| nafamostat | prothrombin | small molecule | NA | drugbank | Blood Vessel[MeSHID:D001808] Blood coagulation[MeSHID:D001777] Cell Respiration[MeSHID:D019069] Hemorrhage[MeSHID:D006470] Tissue membrane[MeSHID:D008566] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Middle East Respiratory Syndrome[MeSHID:D018352] Disease[MeSHID:D004194] |
NA | investigational | inhibitor |
| nafamostat | intercellular adhesion molecule 1 | small molecule | NA | drugbank | Blood Vessel[MeSHID:D001808] Blood coagulation[MeSHID:D001777] Cell Respiration[MeSHID:D019069] Hemorrhage[MeSHID:D006470] Tissue membrane[MeSHID:D008566] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] Pancreatitis[MeSHID:D010195] |
NA | investigational | inhibitor |
| nafamostat | intercellular adhesion molecule 1 | small molecule | NA | drugbank | Blood Vessel[MeSHID:D001808] Blood coagulation[MeSHID:D001777] Cell Respiration[MeSHID:D019069] Hemorrhage[MeSHID:D006470] Tissue membrane[MeSHID:D008566] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Middle East Respiratory Syndrome[MeSHID:D018352] Disease[MeSHID:D004194] |
NA | investigational | inhibitor |
| nafamostat | kallikrein-1 | small molecule | NA | drugbank | Blood Vessel[MeSHID:D001808] Blood coagulation[MeSHID:D001777] Cell Respiration[MeSHID:D019069] Hemorrhage[MeSHID:D006470] Tissue membrane[MeSHID:D008566] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] Pancreatitis[MeSHID:D010195] |
NA | investigational | inhibitor |
| nafamostat | kallikrein-1 | small molecule | NA | drugbank | Blood Vessel[MeSHID:D001808] Blood coagulation[MeSHID:D001777] Cell Respiration[MeSHID:D019069] Hemorrhage[MeSHID:D006470] Tissue membrane[MeSHID:D008566] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Middle East Respiratory Syndrome[MeSHID:D018352] Disease[MeSHID:D004194] |
NA | investigational | inhibitor |
| nafamostat | trypsin-1 | small molecule | NA | drugbank , DGIDB | Blood Vessel[MeSHID:D001808] Blood coagulation[MeSHID:D001777] Cell Respiration[MeSHID:D019069] Hemorrhage[MeSHID:D006470] Tissue membrane[MeSHID:D008566] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] Pancreatitis[MeSHID:D010195] |
1.65 | investigational | inhibitor |
| nafamostat | trypsin-1 | small molecule | NA | drugbank , DGIDB | Blood Vessel[MeSHID:D001808] Blood coagulation[MeSHID:D001777] Cell Respiration[MeSHID:D019069] Hemorrhage[MeSHID:D006470] Tissue membrane[MeSHID:D008566] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Middle East Respiratory Syndrome[MeSHID:D018352] Disease[MeSHID:D004194] |
1.65 | investigational | inhibitor |
| nafamostat | tumor necrosis factor | NA | Successful target | TTD , DGIDB | Blood Vessel[MeSHID:D001808] Blood coagulation[MeSHID:D001777] Cell Respiration[MeSHID:D019069] Hemorrhage[MeSHID:D006470] Tissue membrane[MeSHID:D008566] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Middle East Respiratory Syndrome[MeSHID:D018352] Disease[MeSHID:D004194] |
0.09 | approved | unknown |
| nafamostat | tumor necrosis factor | NA | Successful target | TTD , DGIDB | Blood Vessel[MeSHID:D001808] Blood coagulation[MeSHID:D001777] Cell Respiration[MeSHID:D019069] Hemorrhage[MeSHID:D006470] Tissue membrane[MeSHID:D008566] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Sepsis[MeSHID:D018805] Pancreatitis[MeSHID:D010195] |
0.09 | approved | unknown |
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