Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
moxetumomab pasudotox b-cell receptor cd22 biotech Successful target TTD , drugbank , DGIDB Lymphocyte[MeSHID:D008214]
Malignant Neoplasms[MeSHID:D009369]
Renal Insufficiency[MeSHID:D051437]
Splenomegaly[MeSHID:D013163]
Relapse[MeSHID:D012008]
Hypertrichosis[MeSHID:D006983]
Hirsutism[MeSHID:D006628]
leukemia[MeSHID:D007938]
Hair[MeSHID:D006197]
Hepatomegaly[MeSHID:D006529]
Hairy Cell Leukemia[MeSHID:D007943]
B-Lymphocytes[MeSHID:D001402]
Cell Surface Extensions[MeSHID:D022081]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Hematologic Neoplasms[MeSHID:D019337]		 NA approved,investigational binder
moxetumomab pasudotox b-cell receptor cd22 biotech Successful target TTD , drugbank , DGIDB Lymphocyte[MeSHID:D008214]
Malignant Neoplasms[MeSHID:D009369]
Renal Insufficiency[MeSHID:D051437]
Splenomegaly[MeSHID:D013163]
Relapse[MeSHID:D012008]
Hypertrichosis[MeSHID:D006983]
Hirsutism[MeSHID:D006628]
leukemia[MeSHID:D007938]
Hair[MeSHID:D006197]
Hepatomegaly[MeSHID:D006529]
Hairy Cell Leukemia[MeSHID:D007943]
B-Lymphocytes[MeSHID:D001402]
Cell Surface Extensions[MeSHID:D022081]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Hematologic Neoplasms[MeSHID:D019337]		 31.83 approved,investigational binder
moxetumomab pasudotox b-cell receptor cd22 biotech Successful target TTD , drugbank , DGIDB Lymphocyte[MeSHID:D008214]
Malignant Neoplasms[MeSHID:D009369]
Renal Insufficiency[MeSHID:D051437]
Splenomegaly[MeSHID:D013163]
Relapse[MeSHID:D012008]
Hypertrichosis[MeSHID:D006983]
Hirsutism[MeSHID:D006628]
leukemia[MeSHID:D007938]
Hair[MeSHID:D006197]
Hepatomegaly[MeSHID:D006529]
Hairy Cell Leukemia[MeSHID:D007943]
B-Lymphocytes[MeSHID:D001402]
Cell Surface Extensions[MeSHID:D022081]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Hematologic Neoplasms[MeSHID:D019337]		 NA approved,investigational binder,antibody
moxetumomab pasudotox elongation factor 2 biotech NA drugbank Lymphocyte[MeSHID:D008214]
Malignant Neoplasms[MeSHID:D009369]
Renal Insufficiency[MeSHID:D051437]
Splenomegaly[MeSHID:D013163]
Relapse[MeSHID:D012008]
Hypertrichosis[MeSHID:D006983]
Hirsutism[MeSHID:D006628]
leukemia[MeSHID:D007938]
Hair[MeSHID:D006197]
Hepatomegaly[MeSHID:D006529]
Hairy Cell Leukemia[MeSHID:D007943]
B-Lymphocytes[MeSHID:D001402]
Cell Surface Extensions[MeSHID:D022081]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Hematologic Neoplasms[MeSHID:D019337]		 NA approved,investigational inactivator
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