| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| modafinil | alpha-1b adrenergic receptor | small molecule | NA | drugbank | Narcolepsy[MeSHID:D009290] Wakefulness[MeSHID:D014851] Hypersomnia[MeSHID:D006970] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Bipolar Disorder[MeSHID:D001714] Brain Injuries[MeSHID:D001930] |
NA | approved,investigational | partial agonist |
| modafinil | dopamine transporter | NA | Successful target | TTD , DGIDB | Narcolepsy[MeSHID:D009290] Wakefulness[MeSHID:D014851] Hypersomnia[MeSHID:D006970] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Bipolar Disorder[MeSHID:D001714] Brain Injuries[MeSHID:D001930] |
0.85 | approved | inhibitor |
| modafinil | sodium-dependent dopamine transporter | small molecule | NA | drugbank , DGIDB | Narcolepsy[MeSHID:D009290] Wakefulness[MeSHID:D014851] Hypersomnia[MeSHID:D006970] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Bipolar Disorder[MeSHID:D001714] Brain Injuries[MeSHID:D001930] |
0.85 | approved,investigational | inhibitor |
| modafinil | dopamine transporter | NA | Successful target | TTD , DGIDB | Narcolepsy[MeSHID:D009290] Wakefulness[MeSHID:D014851] Hypersomnia[MeSHID:D006970] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Bipolar Disorder[MeSHID:D001714] Brain Injuries[MeSHID:D001930] |
0.85 | approved | unknown |
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