Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
mk-2461 fibroblast growth factor receptor 1 NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.1 phase 1/2 inhibitor
mk-2461 fibroblast growth factor receptor 1 NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.1 phase 1/2 unknown
mk-2461 fibroblast growth factor receptor 2 NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.18 phase 1/2 unknown
mk-2461 fibroblast growth factor receptor 2 NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.18 phase 1/2 inhibitor
mk-2461 fibroblast growth factor receptor 3 NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.15 phase 1/2 inhibitor
mk-2461 fibroblast growth factor receptor 3 NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.15 phase 1/2 unknown
mk-2461 vegfr1 messenger rna NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.05 phase 1/2 inhibitor
mk-2461 fms-like tyrosine kinase 3 NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.09 phase 1/2 inhibitor
mk-2461 fms-like tyrosine kinase 3 NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.09 phase 1/2 unknown
mk-2461 vascular endothelial growth factor receptor 3 NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.1 phase 1/2 inhibitor
mk-2461 vascular endothelial growth factor receptor 3 NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.1 phase 1/2 unknown
mk-2461 vascular endothelial growth factor receptor 2 NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.07 phase 1/2 inhibitor
mk-2461 vascular endothelial growth factor receptor 2 NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.07 phase 1/2 unknown
mk-2461 tyrosine-protein kinase mer NA Clinical trial target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
1.52 phase 1/2 inhibitor
mk-2461 tyrosine-protein kinase mer NA Clinical trial target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
1.52 phase 1/2 unknown
mk-2461 proto-oncogene c-met NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.17 phase 1/2 unknown
mk-2461 proto-oncogene c-met NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.17 phase 1/2 inhibitor
mk-2461 macrophage-stimulating protein receptor NA Clinical trial target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.35 phase 1/2 unknown
mk-2461 macrophage-stimulating protein receptor NA Clinical trial target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.35 phase 1/2 inhibitor
mk-2461 bdnf/nt-3 growth factors receptor NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.2 phase 1/2 unknown
mk-2461 bdnf/nt-3 growth factors receptor NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.2 phase 1/2 inhibitor
mk-2461 nt-3 growth factor receptor NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.13 phase 1/2 unknown
mk-2461 platelet-derived growth factor receptor beta NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.12 phase 1/2 inhibitor
mk-2461 platelet-derived growth factor receptor beta NA Successful target TTD , DGIDB Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
0.12 phase 1/2 unknown
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