Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
mitotane androgen receptor small molecule NA drugbank Tumors of Adrenal Cortex[MeSHID:D000306]
Cushing Syndrome[MeSHID:D003480]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Adrenocortical carcinoma[MeSHID:D018268]		 NA approved antagonist
mitotane cytochrome p450 11b1, mitochondrial small molecule NA drugbank , DGIDB Tumors of Adrenal Cortex[MeSHID:D000306]
Cushing Syndrome[MeSHID:D003480]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Adrenocortical carcinoma[MeSHID:D018268]		 5.97 approved inducer,inhibitor
mitotane estrogen receptor alpha small molecule NA drugbank , DGIDB Tumors of Adrenal Cortex[MeSHID:D000306]
Cushing Syndrome[MeSHID:D003480]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Adrenocortical carcinoma[MeSHID:D018268]		 0.08 approved unknown
mitotane estrogen receptor NA Successful target TTD , DGIDB Tumors of Adrenal Cortex[MeSHID:D000306]
Cushing Syndrome[MeSHID:D003480]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Adrenocortical carcinoma[MeSHID:D018268]		 0.08 approved unknown
mitotane adrenodoxin, mitochondrial small molecule NA drugbank Tumors of Adrenal Cortex[MeSHID:D000306]
Cushing Syndrome[MeSHID:D003480]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Adrenocortical carcinoma[MeSHID:D018268]		 NA approved unknown
mitotane progesterone receptor small molecule NA drugbank Tumors of Adrenal Cortex[MeSHID:D000306]
Cushing Syndrome[MeSHID:D003480]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Adrenocortical carcinoma[MeSHID:D018268]		 NA approved unknown
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