Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
mirtazapine alpha-1 adrenergic receptors small molecule NA drugbank Major Depressive Disorder[MeSHID:D003865]
Hot flushes[MeSHID:D019584]
Unipolar Depression[MeSHID:D003866]
Disease[MeSHID:D004194]
Dysthymic Disorder[MeSHID:D019263]
Tension Headache[MeSHID:D018781]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Sleep Disorders[MeSHID:D012893]
Panic Disorder[MeSHID:D016584]
Off-Label Use[MeSHID:D056687]
Substance abuse problem[MeSHID:D019966]
Anxiety Disorders[MeSHID:D001008]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Mental Depression[MeSHID:D003863]
Depressive disorder[MeSHID:D003866]		 NA approved antagonist
mirtazapine alpha-1 adrenergic receptors small molecule NA drugbank Major Depressive Disorder[MeSHID:D003865]
Hot flushes[MeSHID:D019584]
Unipolar Depression[MeSHID:D003866]
Disease[MeSHID:D004194]
Dysthymic Disorder[MeSHID:D019263]
Tension Headache[MeSHID:D018781]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Sleep Disorders[MeSHID:D012893]
Panic Disorder[MeSHID:D016584]
Off-Label Use[MeSHID:D056687]
Substance abuse problem[MeSHID:D019966]
Anxiety Disorders[MeSHID:D001008]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Mental Depression[MeSHID:D003863]
Depressive disorder[MeSHID:D003866]		 NA approved antagonist
mirtazapine alpha-1 adrenergic receptors small molecule NA drugbank Major Depressive Disorder[MeSHID:D003865]
Hot flushes[MeSHID:D019584]
Unipolar Depression[MeSHID:D003866]
Disease[MeSHID:D004194]
Dysthymic Disorder[MeSHID:D019263]
Tension Headache[MeSHID:D018781]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Sleep Disorders[MeSHID:D012893]
Panic Disorder[MeSHID:D016584]
Off-Label Use[MeSHID:D056687]
Substance abuse problem[MeSHID:D019966]
Anxiety Disorders[MeSHID:D001008]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Mental Depression[MeSHID:D003863]
Depressive disorder[MeSHID:D003866]		 NA approved antagonist
mirtazapine alpha-2a adrenergic receptor small molecule NA drugbank , DGIDB Major Depressive Disorder[MeSHID:D003865]
Hot flushes[MeSHID:D019584]
Unipolar Depression[MeSHID:D003866]
Disease[MeSHID:D004194]
Dysthymic Disorder[MeSHID:D019263]
Tension Headache[MeSHID:D018781]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Sleep Disorders[MeSHID:D012893]
Panic Disorder[MeSHID:D016584]
Off-Label Use[MeSHID:D056687]
Substance abuse problem[MeSHID:D019966]
Anxiety Disorders[MeSHID:D001008]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Mental Depression[MeSHID:D003863]
Depressive disorder[MeSHID:D003866]		 0.51 approved antagonist
mirtazapine histamine h1 receptor small molecule NA drugbank Major Depressive Disorder[MeSHID:D003865]
Hot flushes[MeSHID:D019584]
Unipolar Depression[MeSHID:D003866]
Disease[MeSHID:D004194]
Dysthymic Disorder[MeSHID:D019263]
Tension Headache[MeSHID:D018781]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Sleep Disorders[MeSHID:D012893]
Panic Disorder[MeSHID:D016584]
Off-Label Use[MeSHID:D056687]
Substance abuse problem[MeSHID:D019966]
Anxiety Disorders[MeSHID:D001008]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Mental Depression[MeSHID:D003863]
Depressive disorder[MeSHID:D003866]		 NA approved antagonist
mirtazapine 5-hydroxytryptamine receptor 2a small molecule NA drugbank , DGIDB Major Depressive Disorder[MeSHID:D003865]
Hot flushes[MeSHID:D019584]
Unipolar Depression[MeSHID:D003866]
Disease[MeSHID:D004194]
Dysthymic Disorder[MeSHID:D019263]
Tension Headache[MeSHID:D018781]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Sleep Disorders[MeSHID:D012893]
Panic Disorder[MeSHID:D016584]
Off-Label Use[MeSHID:D056687]
Substance abuse problem[MeSHID:D019966]
Anxiety Disorders[MeSHID:D001008]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Mental Depression[MeSHID:D003863]
Depressive disorder[MeSHID:D003866]		 0.28 approved antagonist
mirtazapine 5-ht 2c receptor NA Successful target TTD , DGIDB Major Depressive Disorder[MeSHID:D003865]
Hot flushes[MeSHID:D019584]
Unipolar Depression[MeSHID:D003866]
Disease[MeSHID:D004194]
Dysthymic Disorder[MeSHID:D019263]
Tension Headache[MeSHID:D018781]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Sleep Disorders[MeSHID:D012893]
Panic Disorder[MeSHID:D016584]
Off-Label Use[MeSHID:D056687]
Substance abuse problem[MeSHID:D019966]
Anxiety Disorders[MeSHID:D001008]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Mental Depression[MeSHID:D003863]
Depressive disorder[MeSHID:D003866]		 0.35 approved unknown
mirtazapine 5-hydroxytryptamine receptor 2c small molecule NA drugbank , DGIDB Major Depressive Disorder[MeSHID:D003865]
Hot flushes[MeSHID:D019584]
Unipolar Depression[MeSHID:D003866]
Disease[MeSHID:D004194]
Dysthymic Disorder[MeSHID:D019263]
Tension Headache[MeSHID:D018781]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Sleep Disorders[MeSHID:D012893]
Panic Disorder[MeSHID:D016584]
Off-Label Use[MeSHID:D056687]
Substance abuse problem[MeSHID:D019966]
Anxiety Disorders[MeSHID:D001008]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Mental Depression[MeSHID:D003863]
Depressive disorder[MeSHID:D003866]		 0.35 approved antagonist
mirtazapine 5-ht 2c receptor NA Successful target TTD , DGIDB Major Depressive Disorder[MeSHID:D003865]
Hot flushes[MeSHID:D019584]
Unipolar Depression[MeSHID:D003866]
Disease[MeSHID:D004194]
Dysthymic Disorder[MeSHID:D019263]
Tension Headache[MeSHID:D018781]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Sleep Disorders[MeSHID:D012893]
Panic Disorder[MeSHID:D016584]
Off-Label Use[MeSHID:D056687]
Substance abuse problem[MeSHID:D019966]
Anxiety Disorders[MeSHID:D001008]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Mental Depression[MeSHID:D003863]
Depressive disorder[MeSHID:D003866]		 0.35 approved antagonist
mirtazapine 5ht3 serotonin receptor small molecule NA drugbank Major Depressive Disorder[MeSHID:D003865]
Hot flushes[MeSHID:D019584]
Unipolar Depression[MeSHID:D003866]
Disease[MeSHID:D004194]
Dysthymic Disorder[MeSHID:D019263]
Tension Headache[MeSHID:D018781]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Sleep Disorders[MeSHID:D012893]
Panic Disorder[MeSHID:D016584]
Off-Label Use[MeSHID:D056687]
Substance abuse problem[MeSHID:D019966]
Anxiety Disorders[MeSHID:D001008]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Mental Depression[MeSHID:D003863]
Depressive disorder[MeSHID:D003866]		 NA approved antagonist
mirtazapine kappa-type opioid receptor small molecule NA drugbank Major Depressive Disorder[MeSHID:D003865]
Hot flushes[MeSHID:D019584]
Unipolar Depression[MeSHID:D003866]
Disease[MeSHID:D004194]
Dysthymic Disorder[MeSHID:D019263]
Tension Headache[MeSHID:D018781]
Post-Traumatic Stress Disorder[MeSHID:D013313]
Sleep Disorders[MeSHID:D012893]
Panic Disorder[MeSHID:D016584]
Off-Label Use[MeSHID:D056687]
Substance abuse problem[MeSHID:D019966]
Anxiety Disorders[MeSHID:D001008]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Mental Depression[MeSHID:D003863]
Depressive disorder[MeSHID:D003866]		 NA approved agonist
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