| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| minaprine | acetylcholinesterase | small molecule | NA | drugbank | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| minaprine | muscarinic acetylcholine receptor m1 | small molecule | NA | drugbank | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | agonist |
| minaprine | dopamine d1 receptor | small molecule | NA | drugbank , DGIDB | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.32 | approved | agonist |
| minaprine | dopamine d2 receptor | small molecule | NA | drugbank , DGIDB | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.3 | approved | agonist |
| minaprine | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank , DGIDB | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.44 | approved | antagonist |
| minaprine | 5-hydroxytryptamine receptor 2b | small molecule | NA | drugbank , DGIDB | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.25 | approved | antagonist |
| minaprine | 5-ht 2b receptor | NA | Successful target | TTD , DGIDB | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
1.25 | approved | unknown |
| minaprine | 5-hydroxytryptamine receptor 2c | small molecule | NA | drugbank , DGIDB | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.66 | approved | antagonist |
| minaprine | amine oxidase [flavin-containing] a | small molecule | NA | drugbank | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| minaprine | sodium-dependent serotonin transporter | small molecule | NA | drugbank , DGIDB | Mental Depression[MeSHID:D003863] Depressive disorder[MeSHID:D003866] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.9 | approved | inhibitor |
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