Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
mifepristone prostate-specific antigen small molecule NA drugbank , DGIDB Hyperglycemia[MeSHID:D006943]
Operative Surgical Procedures[MeSHID:D013514]
Impaired glucose tolerance[MeSHID:D018149]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Diabetes Mellitus
Non-Insulin-Dependent[MeSHID:D003924]
Cushing Syndrome[MeSHID:D003480]
Adrenal Gland Hyperfunction[MeSHID:D000308]
ADULT SYNDROME[MeSHID:C538052]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Pituitary-dependent Cushing's disease[MeSHID:D047748]		 0.53 approved,investigational unknown
mifepristone nuclear receptor subfamily 1 group i member 2 small molecule NA drugbank , DGIDB Hyperglycemia[MeSHID:D006943]
Operative Surgical Procedures[MeSHID:D013514]
Impaired glucose tolerance[MeSHID:D018149]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Diabetes Mellitus
Non-Insulin-Dependent[MeSHID:D003924]
Cushing Syndrome[MeSHID:D003480]
Adrenal Gland Hyperfunction[MeSHID:D000308]
ADULT SYNDROME[MeSHID:C538052]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Pituitary-dependent Cushing's disease[MeSHID:D047748]		 0.06 approved,investigational agonist
mifepristone glucocorticoid receptor small molecule Successful target TTD , drugbank , DGIDB Hyperglycemia[MeSHID:D006943]
Operative Surgical Procedures[MeSHID:D013514]
Impaired glucose tolerance[MeSHID:D018149]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Diabetes Mellitus
Non-Insulin-Dependent[MeSHID:D003924]
Cushing Syndrome[MeSHID:D003480]
Adrenal Gland Hyperfunction[MeSHID:D000308]
ADULT SYNDROME[MeSHID:C538052]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Pituitary-dependent Cushing's disease[MeSHID:D047748]		 0.24 approved,investigational antagonist
mifepristone progesterone receptor small molecule NA drugbank , DGIDB Hyperglycemia[MeSHID:D006943]
Operative Surgical Procedures[MeSHID:D013514]
Impaired glucose tolerance[MeSHID:D018149]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Diabetes Mellitus
Non-Insulin-Dependent[MeSHID:D003924]
Cushing Syndrome[MeSHID:D003480]
Adrenal Gland Hyperfunction[MeSHID:D000308]
ADULT SYNDROME[MeSHID:C538052]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Pituitary-dependent Cushing's disease[MeSHID:D047748]		 0.57 approved,investigational antagonist
mifepristone progesterone receptor small molecule NA drugbank , DGIDB Hyperglycemia[MeSHID:D006943]
Operative Surgical Procedures[MeSHID:D013514]
Impaired glucose tolerance[MeSHID:D018149]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Diabetes Mellitus
Non-Insulin-Dependent[MeSHID:D003924]
Cushing Syndrome[MeSHID:D003480]
Adrenal Gland Hyperfunction[MeSHID:D000308]
ADULT SYNDROME[MeSHID:C538052]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Pituitary-dependent Cushing's disease[MeSHID:D047748]		 0.57 approved,investigational antagonist,agonist
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