| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| metharbital | neuronal acetylcholine receptor subunit alpha-4 | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.39 | withdrawn | antagonist |
| metharbital | neuronal acetylcholine receptor subunit alpha-7 | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.36 | withdrawn | antagonist |
| metharbital | gamma-aminobutyric acid receptor subunit alpha-1 | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.33 | withdrawn | potentiator,positive modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.33 | withdrawn | positive allosteric modulator |
| metharbital | gamma-aminobutyric acid receptor subunit alpha-1 | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.33 | withdrawn | potentiator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.33 | withdrawn | positive allosteric modulator,positive modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.19 | withdrawn | positive allosteric modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.19 | withdrawn | positive allosteric modulator,positive modulator |
| metharbital | gamma-aminobutyric acid receptor subunit alpha-2 | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.19 | withdrawn | potentiator |
| metharbital | gamma-aminobutyric acid receptor subunit alpha-2 | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.19 | withdrawn | potentiator,positive modulator |
| metharbital | gamma-aminobutyric acid receptor subunit alpha-3 | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.19 | withdrawn | potentiator |
| metharbital | gamma-aminobutyric acid receptor subunit alpha-3 | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.19 | withdrawn | potentiator,positive modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.19 | withdrawn | positive allosteric modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.19 | withdrawn | positive allosteric modulator,positive modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | withdrawn | positive allosteric modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | withdrawn | positive allosteric modulator,positive modulator |
| metharbital | gamma-aminobutyric acid receptor subunit alpha-4 | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | withdrawn | potentiator,positive modulator |
| metharbital | gamma-aminobutyric acid receptor subunit alpha-4 | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | withdrawn | potentiator |
| metharbital | gamma-aminobutyric acid receptor subunit alpha-5 | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.2 | withdrawn | potentiator |
| metharbital | gamma-aminobutyric acid receptor subunit alpha-5 | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.2 | withdrawn | potentiator,positive modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.2 | withdrawn | positive allosteric modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.2 | withdrawn | positive allosteric modulator,positive modulator |
| metharbital | gamma-aminobutyric acid receptor subunit alpha-6 | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.22 | withdrawn | potentiator,positive modulator |
| metharbital | gamma-aminobutyric acid receptor subunit alpha-6 | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.22 | withdrawn | potentiator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.22 | withdrawn | positive allosteric modulator,positive modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.22 | withdrawn | positive allosteric modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | withdrawn | positive allosteric modulator,positive modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | withdrawn | positive allosteric modulator,positive modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | withdrawn | positive allosteric modulator,positive modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | withdrawn | positive allosteric modulator,positive modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | withdrawn | positive allosteric modulator,positive modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | withdrawn | positive allosteric modulator,positive modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | withdrawn | positive allosteric modulator,positive modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.09 | withdrawn | positive allosteric modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.09 | withdrawn | positive allosteric modulator,positive modulator |
| metharbital | gaba(a) receptor gamma-3 | NA | Successful target | TTD , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.09 | approved | unknown |
| metharbital | gaba(a) receptor gamma-3 | NA | Successful target | TTD , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.09 | approved | positive modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.05 | withdrawn | positive allosteric modulator,positive modulator |
| metharbital | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.06 | withdrawn | positive allosteric modulator,positive modulator |
| metharbital | glutamate receptor 2 | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.39 | withdrawn | antagonist |
| metharbital | glutamate receptor ionotropic, kainate 2 | small molecule | NA | drugbank , DGIDB | Epilepsy[MeSHID:D004827] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.85 | withdrawn | antagonist |
| click here to return to the previous page | ||||||||