Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
methantheline muscarinic acetylcholine receptor m1 small molecule NA drugbank , DGIDB Reflex action[MeSHID:D012018]
Neurogenic Urinary Bladder[MeSHID:D001750]
Gastritis[MeSHID:D005756]
Irritable Bowel Syndrome[MeSHID:D043183]
Biliary Dyskinesia[MeSHID:D001657]
Peptic Ulcer[MeSHID:D010437]
Pancreatitis[MeSHID:D010195]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.96 approved,investigational antagonist
methantheline muscarinic acetylcholine receptor m2 small molecule NA drugbank Reflex action[MeSHID:D012018]
Neurogenic Urinary Bladder[MeSHID:D001750]
Gastritis[MeSHID:D005756]
Irritable Bowel Syndrome[MeSHID:D043183]
Biliary Dyskinesia[MeSHID:D001657]
Peptic Ulcer[MeSHID:D010437]
Pancreatitis[MeSHID:D010195]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,investigational unknown
methantheline muscarinic acetylcholine receptor m3 small molecule NA drugbank Reflex action[MeSHID:D012018]
Neurogenic Urinary Bladder[MeSHID:D001750]
Gastritis[MeSHID:D005756]
Irritable Bowel Syndrome[MeSHID:D043183]
Biliary Dyskinesia[MeSHID:D001657]
Peptic Ulcer[MeSHID:D010437]
Pancreatitis[MeSHID:D010195]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,investigational unknown
methantheline muscarinic acetylcholine receptor m4 small molecule NA drugbank Reflex action[MeSHID:D012018]
Neurogenic Urinary Bladder[MeSHID:D001750]
Gastritis[MeSHID:D005756]
Irritable Bowel Syndrome[MeSHID:D043183]
Biliary Dyskinesia[MeSHID:D001657]
Peptic Ulcer[MeSHID:D010437]
Pancreatitis[MeSHID:D010195]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,investigational unknown
methantheline muscarinic acetylcholine receptor m5 small molecule Successful target TTD , drugbank , DGIDB Reflex action[MeSHID:D012018]
Neurogenic Urinary Bladder[MeSHID:D001750]
Gastritis[MeSHID:D005756]
Irritable Bowel Syndrome[MeSHID:D043183]
Biliary Dyskinesia[MeSHID:D001657]
Peptic Ulcer[MeSHID:D010437]
Pancreatitis[MeSHID:D010195]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.66 approved,investigational unknown
methantheline histamine h2 receptor small molecule NA drugbank Reflex action[MeSHID:D012018]
Neurogenic Urinary Bladder[MeSHID:D001750]
Gastritis[MeSHID:D005756]
Irritable Bowel Syndrome[MeSHID:D043183]
Biliary Dyskinesia[MeSHID:D001657]
Peptic Ulcer[MeSHID:D010437]
Pancreatitis[MeSHID:D010195]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,investigational antagonist
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