| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| mesalazine | arachidonate 5-lipoxygenase | small molecule | NA | drugbank , DGIDB | Crohn's disease of large bowel[MeSHID:D003424] ileum[MeSHID:D007082] Ulcerative Colitis[MeSHID:D003093] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.64 | approved | inhibitor |
| mesalazine | inhibitor of nuclear factor kappa-b kinase subunit alpha | small molecule | NA | drugbank | Crohn's disease of large bowel[MeSHID:D003424] ileum[MeSHID:D007082] Ulcerative Colitis[MeSHID:D003093] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| mesalazine | inhibitor of nuclear factor kappa-b kinase subunit beta | small molecule | NA | drugbank | Crohn's disease of large bowel[MeSHID:D003424] ileum[MeSHID:D007082] Ulcerative Colitis[MeSHID:D003093] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | inhibitor |
| mesalazine | myeloperoxidase | small molecule | NA | drugbank | Crohn's disease of large bowel[MeSHID:D003424] ileum[MeSHID:D007082] Ulcerative Colitis[MeSHID:D003093] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved | unknown |
| mesalazine | peroxisome proliferator-activated receptor gamma | small molecule | NA | drugbank , DGIDB | Crohn's disease of large bowel[MeSHID:D003424] ileum[MeSHID:D007082] Ulcerative Colitis[MeSHID:D003093] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.16 | approved | agonist |
| mesalazine | prostaglandin g/h synthase 1 | small molecule | Successful target | TTD , drugbank , DGIDB | Crohn's disease of large bowel[MeSHID:D003424] ileum[MeSHID:D007082] Ulcerative Colitis[MeSHID:D003093] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.29 | approved | inhibitor |
| mesalazine | prostaglandin g/h synthase 2 | small molecule | NA | drugbank , DGIDB | Crohn's disease of large bowel[MeSHID:D003424] ileum[MeSHID:D007082] Ulcerative Colitis[MeSHID:D003093] Maintenance[MeSHID:D008283] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.29 | approved | inhibitor |
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