Drug-Target Information | ||||||||
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Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
mercaptopurine | hypoxanthine-guanine phosphoribosyltransferase | small molecule | NA | drugbank , DGIDB | Maintenance[MeSHID:D008283] Lymphoid leukemia[MeSHID:D007945] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] Middle East Respiratory Syndrome[MeSHID:D018352] |
2.65 | approved | inhibitor |
mercaptopurine | hypoxanthine-guanine phosphoribosyltransferase | small molecule | NA | drugbank , DGIDB | Maintenance[MeSHID:D008283] Lymphoid leukemia[MeSHID:D007945] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] Crohn Disease[MeSHID:D003424] |
2.65 | approved | inhibitor |
mercaptopurine | inosine-5'-monophosphate dehydrogenase | small molecule | NA | drugbank , DGIDB | Maintenance[MeSHID:D008283] Lymphoid leukemia[MeSHID:D007945] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] Crohn Disease[MeSHID:D003424] |
0.53 | approved | inhibitor |
mercaptopurine | inosine-5'-monophosphate dehydrogenase 1 | NA | Successful target | TTD , DGIDB | Maintenance[MeSHID:D008283] Lymphoid leukemia[MeSHID:D007945] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] Middle East Respiratory Syndrome[MeSHID:D018352] |
0.53 | approved | unknown |
mercaptopurine | inosine-5'-monophosphate dehydrogenase | small molecule | NA | drugbank , DGIDB | Maintenance[MeSHID:D008283] Lymphoid leukemia[MeSHID:D007945] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] Middle East Respiratory Syndrome[MeSHID:D018352] |
0.53 | approved | inhibitor |
mercaptopurine | inosine-5'-monophosphate dehydrogenase 1 | NA | Successful target | TTD , DGIDB | Maintenance[MeSHID:D008283] Lymphoid leukemia[MeSHID:D007945] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] Crohn Disease[MeSHID:D003424] |
0.53 | approved | unknown |
mercaptopurine | inosine-5'-monophosphate dehydrogenase | small molecule | NA | drugbank | Maintenance[MeSHID:D008283] Lymphoid leukemia[MeSHID:D007945] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] Middle East Respiratory Syndrome[MeSHID:D018352] |
NA | approved | inhibitor |
mercaptopurine | inosine-5'-monophosphate dehydrogenase | small molecule | NA | drugbank | Maintenance[MeSHID:D008283] Lymphoid leukemia[MeSHID:D007945] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] Crohn Disease[MeSHID:D003424] |
NA | approved | inhibitor |
mercaptopurine | amidophosphoribosyltransferase | small molecule | Successful target | TTD , drugbank , DGIDB | Maintenance[MeSHID:D008283] Lymphoid leukemia[MeSHID:D007945] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] Crohn Disease[MeSHID:D003424] |
1.33 | approved | inhibitor |
mercaptopurine | amidophosphoribosyltransferase | small molecule | Successful target | TTD , drugbank , DGIDB | Maintenance[MeSHID:D008283] Lymphoid leukemia[MeSHID:D007945] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] Middle East Respiratory Syndrome[MeSHID:D018352] |
1.33 | approved | inhibitor |
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