Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
medroxyprogesterone acetate p-glycoprotein 1 small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational inhibitor
medroxyprogesterone acetate estrogen receptor alpha small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational agonist
medroxyprogesterone acetate gaba(a) receptor small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational inhibitor
medroxyprogesterone acetate gaba(a) receptor small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational inhibitor
medroxyprogesterone acetate gaba(a) receptor small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational inhibitor
medroxyprogesterone acetate gaba(a) receptor small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational inhibitor
medroxyprogesterone acetate gaba(a) receptor small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational inhibitor
medroxyprogesterone acetate gaba(a) receptor small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational inhibitor
medroxyprogesterone acetate gaba(a) receptor small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational inhibitor
medroxyprogesterone acetate gaba(a) receptor small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational inhibitor
medroxyprogesterone acetate gaba(a) receptor small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational inhibitor
medroxyprogesterone acetate gaba(a) receptor small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational inhibitor
medroxyprogesterone acetate gaba(a) receptor small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational inhibitor
medroxyprogesterone acetate gaba(a) receptor small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational inhibitor
medroxyprogesterone acetate gaba(a) receptor small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational inhibitor
medroxyprogesterone acetate gaba(a) receptor small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational inhibitor
medroxyprogesterone acetate gaba(a) receptor small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational inhibitor
medroxyprogesterone acetate gaba(a) receptor small molecule NA drugbank Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 NA approved,investigational inhibitor
medroxyprogesterone acetate progesterone receptor small molecule NA drugbank , DGIDB Atrophic[MeSHID:D001284]
Vagina[MeSHID:D014621]
Mental concentration[MeSHID:D001288]
Osteoporosis
Postmenopausal[MeSHID:D015663]
Renal Cell Carcinoma[MeSHID:D002292]
Endometrium[MeSHID:D004717]
Endometriosis[MeSHID:D004715]
Pregnancy[MeSHID:D011247]
Neoplasm Metastasis[MeSHID:D009362]
Amenorrhea[MeSHID:D000568]
Endometrial Hyperplasia[MeSHID:D004714]
Pain[MeSHID:D010146]
Endocrine System Diseases[MeSHID:D004700]
Uterine hemorrhage[MeSHID:D014592]
Vulva[MeSHID:D014844]		 0.41 approved,investigational agonist
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