Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
mecamylamine neuronal acetylcholine receptor subunit alpha-2 small molecule NA drugbank , DGIDB Essential Hypertension[MeSHID:D000075222]
Malignant Hypertension[MeSHID:D006974]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 2.55 approved,investigational antagonist,blocker
mecamylamine neuronal acetylcholine receptor subunit alpha-2 small molecule NA drugbank , DGIDB Essential Hypertension[MeSHID:D000075222]
Malignant Hypertension[MeSHID:D006974]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 2.55 approved,investigational antagonist
mecamylamine neuronal acetylcholine receptor subunit alpha-4 small molecule NA drugbank , DGIDB Essential Hypertension[MeSHID:D000075222]
Malignant Hypertension[MeSHID:D006974]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.47 approved,investigational unknown
mecamylamine neuronal acetylcholine receptor subunit alpha-4 small molecule NA drugbank , DGIDB Essential Hypertension[MeSHID:D000075222]
Malignant Hypertension[MeSHID:D006974]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.47 approved,investigational blocker
mecamylamine neuronal acetylcholine receptor subunit alpha-7 small molecule NA drugbank , DGIDB Essential Hypertension[MeSHID:D000075222]
Malignant Hypertension[MeSHID:D006974]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.29 approved,investigational blocker
mecamylamine neuronal acetylcholine receptor subunit beta-2 small molecule NA drugbank Essential Hypertension[MeSHID:D000075222]
Malignant Hypertension[MeSHID:D006974]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,investigational unknown
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