Drug-Target Information | ||||||||
---|---|---|---|---|---|---|---|---|
Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
marimastat | matrix metalloproteinase-1 | NA | Successful target | TTD , DGIDB | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
2.27 | phase 3 | unknown |
marimastat | matrix metalloproteinase-1 | NA | Successful target | TTD , DGIDB | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
2.27 | phase 3 | inhibitor |
marimastat | interstitial collagenase | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
2.27 | investigational | inhibitor |
marimastat | stromelysin-2 | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | antagonist |
marimastat | stromelysin-3 | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | antagonist |
marimastat | macrophage metalloelastase | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | inhibitor |
marimastat | collagenase 3 | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | inhibitor |
marimastat | matrix metalloproteinase-14 | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | inhibitor |
marimastat | matrix metalloproteinase-15 | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | inhibitor |
marimastat | matrix metalloproteinase-16 | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | inhibitor |
marimastat | matrix metalloproteinase-17 | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | inhibitor |
marimastat | matrix metalloproteinase-19 | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | inhibitor |
marimastat | matrix metalloproteinase-2 | NA | Successful target | TTD , DGIDB | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
3.37 | phase 3 | unknown |
marimastat | matrix metalloproteinase-2 | NA | Successful target | TTD , DGIDB | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
3.37 | phase 3 | inhibitor |
marimastat | 72 kda type iv collagenase | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
3.37 | investigational | inhibitor |
marimastat | matrix metalloproteinase-20 | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | inhibitor |
marimastat | matrix metalloproteinase-21 | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | inhibitor |
marimastat | matrix metalloproteinase-23 | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | inhibitor |
marimastat | matrix metalloproteinase-24 | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | inhibitor |
marimastat | matrix metalloproteinase-25 | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | inhibitor |
marimastat | matrix metalloproteinase-26 | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | inhibitor |
marimastat | matrix metalloproteinase-27 | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | inhibitor |
marimastat | matrix metalloproteinase-28 | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | inhibitor |
marimastat | stromelysin-1 | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
2.42 | investigational | antagonist |
marimastat | stromelysin-1 | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
2.42 | investigational | antagonist,inhibitor |
marimastat | matrilysin | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
6.06 | investigational | antagonist,inhibitor |
marimastat | matrix metalloproteinase-7 | NA | Successful target | TTD , DGIDB | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
6.06 | phase 3 | unknown |
marimastat | matrix metalloproteinase-7 | NA | Successful target | TTD , DGIDB | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
6.06 | phase 3 | inhibitor |
marimastat | matrilysin | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
6.06 | investigational | antagonist |
marimastat | neutrophil collagenase | small molecule | NA | drugbank | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
NA | investigational | inhibitor |
marimastat | matrix metalloproteinase-9 | small molecule | NA | drugbank , DGIDB | Malignant Neoplasms[MeSHID:D009369] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of pancreas[MeSHID:D010190] Pancreatic carcinoma[MeSHID:C562463] Malignant neoplasm of lung[MeSHID:D008175] |
3.64 | investigational | inhibitor |
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