Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
macitentan endothelin-1 receptor small molecule NA drugbank , DGIDB Idiopathic pulmonary arterial hypertension[MeSHID:D065627]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Cardiovascular Diseases[MeSHID:D002318]		 12.38 approved antagonist
macitentan endothelin a receptor NA Successful target TTD , DGIDB Idiopathic pulmonary arterial hypertension[MeSHID:D065627]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Cardiovascular Diseases[MeSHID:D002318]		 12.38 approved antagonist
macitentan endothelin a receptor NA Successful target TTD , DGIDB Idiopathic pulmonary arterial hypertension[MeSHID:D065627]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Cardiovascular Diseases[MeSHID:D002318]		 12.38 approved unknown
macitentan endothelin b receptor small molecule Successful target TTD , drugbank , DGIDB Idiopathic pulmonary arterial hypertension[MeSHID:D065627]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Cardiovascular Diseases[MeSHID:D002318]		 22.28 approved antagonist
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