Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
lovastatin histone deacetylase 2 small molecule NA drugbank Diabetes Mellitus[MeSHID:D003920]
Angina
Unstable[MeSHID:D000789]
Cardiovascular Diseases[MeSHID:D002318]
Arteriosclerosis[MeSHID:D001161]
Premature Birth[MeSHID:D047928]
Atherosclerosis[MeSHID:D050197]
Stable angina[MeSHID:D060050]
Myocardial Infarction[MeSHID:D009203]
Disease Progression[MeSHID:D018450]
Dyslipidemias[MeSHID:D050171]
Heterozygote[MeSHID:D006579]
Hypercholesterolemia
Familial[MeSHID:D006938]
Coronary Arteriosclerosis[MeSHID:D003324]
Hypercholesterolemia[MeSHID:D006937]
Prescription of drug (procedure)[MeSHID:D011307]
Disease[MeSHID:D004194]
Diet therapy[MeSHID:D004035]
Coronary heart disease[MeSHID:D003327]
Acute Coronary Syndrome[MeSHID:D054058]
Peripheral Arterial Diseases[MeSHID:D058729]
Neoplasm Metastasis[MeSHID:D009362]
Menarche[MeSHID:D008572]
Cerebrovascular accident[MeSHID:D020521]
Chronic Kidney Diseases[MeSHID:D051436]
Aortic Aneurysm
Abdominal[MeSHID:D017544]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,investigational inhibitor
lovastatin hmg-coa reductase NA Successful target TTD , DGIDB Diabetes Mellitus[MeSHID:D003920]
Angina
Unstable[MeSHID:D000789]
Cardiovascular Diseases[MeSHID:D002318]
Arteriosclerosis[MeSHID:D001161]
Premature Birth[MeSHID:D047928]
Atherosclerosis[MeSHID:D050197]
Stable angina[MeSHID:D060050]
Myocardial Infarction[MeSHID:D009203]
Disease Progression[MeSHID:D018450]
Dyslipidemias[MeSHID:D050171]
Heterozygote[MeSHID:D006579]
Hypercholesterolemia
Familial[MeSHID:D006938]
Coronary Arteriosclerosis[MeSHID:D003324]
Hypercholesterolemia[MeSHID:D006937]
Prescription of drug (procedure)[MeSHID:D011307]
Disease[MeSHID:D004194]
Diet therapy[MeSHID:D004035]
Coronary heart disease[MeSHID:D003327]
Acute Coronary Syndrome[MeSHID:D054058]
Peripheral Arterial Diseases[MeSHID:D058729]
Neoplasm Metastasis[MeSHID:D009362]
Menarche[MeSHID:D008572]
Cerebrovascular accident[MeSHID:D020521]
Chronic Kidney Diseases[MeSHID:D051436]
Aortic Aneurysm
Abdominal[MeSHID:D017544]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 1.7 approved inhibitor
lovastatin hmg-coa reductase NA Successful target TTD , DGIDB Diabetes Mellitus[MeSHID:D003920]
Angina
Unstable[MeSHID:D000789]
Cardiovascular Diseases[MeSHID:D002318]
Arteriosclerosis[MeSHID:D001161]
Premature Birth[MeSHID:D047928]
Atherosclerosis[MeSHID:D050197]
Stable angina[MeSHID:D060050]
Myocardial Infarction[MeSHID:D009203]
Disease Progression[MeSHID:D018450]
Dyslipidemias[MeSHID:D050171]
Heterozygote[MeSHID:D006579]
Hypercholesterolemia
Familial[MeSHID:D006938]
Coronary Arteriosclerosis[MeSHID:D003324]
Hypercholesterolemia[MeSHID:D006937]
Prescription of drug (procedure)[MeSHID:D011307]
Disease[MeSHID:D004194]
Diet therapy[MeSHID:D004035]
Coronary heart disease[MeSHID:D003327]
Acute Coronary Syndrome[MeSHID:D054058]
Peripheral Arterial Diseases[MeSHID:D058729]
Neoplasm Metastasis[MeSHID:D009362]
Menarche[MeSHID:D008572]
Cerebrovascular accident[MeSHID:D020521]
Chronic Kidney Diseases[MeSHID:D051436]
Aortic Aneurysm
Abdominal[MeSHID:D017544]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 1.7 approved unknown
lovastatin 3-hydroxy-3-methylglutaryl-coenzyme a reductase small molecule NA drugbank , DGIDB Diabetes Mellitus[MeSHID:D003920]
Angina
Unstable[MeSHID:D000789]
Cardiovascular Diseases[MeSHID:D002318]
Arteriosclerosis[MeSHID:D001161]
Premature Birth[MeSHID:D047928]
Atherosclerosis[MeSHID:D050197]
Stable angina[MeSHID:D060050]
Myocardial Infarction[MeSHID:D009203]
Disease Progression[MeSHID:D018450]
Dyslipidemias[MeSHID:D050171]
Heterozygote[MeSHID:D006579]
Hypercholesterolemia
Familial[MeSHID:D006938]
Coronary Arteriosclerosis[MeSHID:D003324]
Hypercholesterolemia[MeSHID:D006937]
Prescription of drug (procedure)[MeSHID:D011307]
Disease[MeSHID:D004194]
Diet therapy[MeSHID:D004035]
Coronary heart disease[MeSHID:D003327]
Acute Coronary Syndrome[MeSHID:D054058]
Peripheral Arterial Diseases[MeSHID:D058729]
Neoplasm Metastasis[MeSHID:D009362]
Menarche[MeSHID:D008572]
Cerebrovascular accident[MeSHID:D020521]
Chronic Kidney Diseases[MeSHID:D051436]
Aortic Aneurysm
Abdominal[MeSHID:D017544]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 1.7 approved,investigational inhibitor
lovastatin integrin alpha-l small molecule NA drugbank Diabetes Mellitus[MeSHID:D003920]
Angina
Unstable[MeSHID:D000789]
Cardiovascular Diseases[MeSHID:D002318]
Arteriosclerosis[MeSHID:D001161]
Premature Birth[MeSHID:D047928]
Atherosclerosis[MeSHID:D050197]
Stable angina[MeSHID:D060050]
Myocardial Infarction[MeSHID:D009203]
Disease Progression[MeSHID:D018450]
Dyslipidemias[MeSHID:D050171]
Heterozygote[MeSHID:D006579]
Hypercholesterolemia
Familial[MeSHID:D006938]
Coronary Arteriosclerosis[MeSHID:D003324]
Hypercholesterolemia[MeSHID:D006937]
Prescription of drug (procedure)[MeSHID:D011307]
Disease[MeSHID:D004194]
Diet therapy[MeSHID:D004035]
Coronary heart disease[MeSHID:D003327]
Acute Coronary Syndrome[MeSHID:D054058]
Peripheral Arterial Diseases[MeSHID:D058729]
Neoplasm Metastasis[MeSHID:D009362]
Menarche[MeSHID:D008572]
Cerebrovascular accident[MeSHID:D020521]
Chronic Kidney Diseases[MeSHID:D051436]
Aortic Aneurysm
Abdominal[MeSHID:D017544]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved,investigational inhibitor
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