| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| lorazepam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved | ligand,positive modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved | positive allosteric modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved | positive allosteric modulator,positive modulator |
| lorazepam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.17 | approved | ligand |
| lorazepam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.1 | approved | ligand |
| lorazepam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.1 | approved | ligand,positive modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.1 | approved | positive allosteric modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.1 | approved | positive allosteric modulator,positive modulator |
| lorazepam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.1 | approved | ligand |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.1 | approved | positive allosteric modulator,positive modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.1 | approved | positive allosteric modulator |
| lorazepam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.1 | approved | ligand,positive modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved | positive allosteric modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved | positive allosteric modulator,positive modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.1 | approved | positive allosteric modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.1 | approved | positive allosteric modulator,positive modulator |
| lorazepam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.1 | approved | ligand |
| lorazepam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.1 | approved | ligand,positive modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved | positive allosteric modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved | positive allosteric modulator,positive modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.13 | approved | positive allosteric modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.13 | approved | positive allosteric modulator,positive modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.12 | approved | positive allosteric modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.12 | approved | positive allosteric modulator,positive modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.13 | approved | positive allosteric modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.13 | approved | positive allosteric modulator,positive modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.13 | approved | positive allosteric modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.13 | approved | positive allosteric modulator,positive modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.14 | approved | positive allosteric modulator,positive modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.14 | approved | positive allosteric modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.13 | approved | positive allosteric modulator,positive modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.13 | approved | positive allosteric modulator |
| lorazepam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.13 | approved | ligand,positive modulator |
| lorazepam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.13 | approved | ligand |
| lorazepam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.08 | approved | ligand,positive modulator |
| lorazepam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.08 | approved | ligand |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.08 | approved | positive allosteric modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.08 | approved | positive allosteric modulator,positive modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved | positive allosteric modulator |
| lorazepam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved | ligand,positive modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved | positive allosteric modulator,positive modulator |
| lorazepam | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.11 | approved | ligand |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.14 | approved | positive allosteric modulator,positive modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.14 | approved | positive allosteric modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.15 | approved | positive allosteric modulator |
| lorazepam | gaba(a) receptor | small molecule | NA | drugbank , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.15 | approved | positive allosteric modulator,positive modulator |
| lorazepam | translocator protein | NA | Successful target | TTD , DGIDB | Spasm[MeSHID:D013035] Status Epilepticus[MeSHID:D013226] Nausea[MeSHID:D009325] Amnesia[MeSHID:D000647] Vomiting[MeSHID:D014839] Delirium[MeSHID:D003693] Anxiety[MeSHID:D001007] Panic Disorder[MeSHID:D016584] Anxiety Disorders[MeSHID:D001008] Depressive Symptoms[MeSHID:D003863] Substance Withdrawal Syndrome[MeSHID:D013375] Alcohol Withdrawal Delirium[MeSHID:D000430] Catatonia[MeSHID:D002389] Sleeplessness[MeSHID:D007319] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.57 | approved | unknown |
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