Drug-Target Information | ||||||||
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Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
liothyronine | proliferating cell nuclear antigen | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Pituitary Gland[MeSHID:D010902] Operative Surgical Procedures[MeSHID:D013514] Thyroid carcinoma[MeSHID:D013964] Hyperthyroidism[MeSHID:D006980] Constipation[MeSHID:D003248] Desiccation[MeSHID:D003890] Pituitary Diseases[MeSHID:D010900] Pallor[MeSHID:D010167] Term Birth[MeSHID:D047929] Hypothyroidism[MeSHID:D007037] Thyroid Gland[MeSHID:D013961] Endemic goiter[MeSHID:D006043] Neoplasm Metastasis[MeSHID:D009362] Hypothalamic structure[MeSHID:D007031] Plasma[MeSHID:D010949] Subacute thyroiditis[MeSHID:D013968] Voice[MeSHID:D014831] Hair[MeSHID:D006197] Lethargy[MeSHID:D053609] Drowsiness[MeSHID:D012894] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
NA | approved,vet_approved | antagonist |
liothyronine | thyroid hormone receptor alpha | small molecule | Successful target | TTD , drugbank , DGIDB | Disease Management[MeSHID:D019468] Pituitary Gland[MeSHID:D010902] Operative Surgical Procedures[MeSHID:D013514] Thyroid carcinoma[MeSHID:D013964] Hyperthyroidism[MeSHID:D006980] Constipation[MeSHID:D003248] Desiccation[MeSHID:D003890] Pituitary Diseases[MeSHID:D010900] Pallor[MeSHID:D010167] Term Birth[MeSHID:D047929] Hypothyroidism[MeSHID:D007037] Thyroid Gland[MeSHID:D013961] Endemic goiter[MeSHID:D006043] Neoplasm Metastasis[MeSHID:D009362] Hypothalamic structure[MeSHID:D007031] Plasma[MeSHID:D010949] Subacute thyroiditis[MeSHID:D013968] Voice[MeSHID:D014831] Hair[MeSHID:D006197] Lethargy[MeSHID:D053609] Drowsiness[MeSHID:D012894] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
7.96 | approved,vet_approved | agonist |
liothyronine | thyroid hormone receptor beta | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Pituitary Gland[MeSHID:D010902] Operative Surgical Procedures[MeSHID:D013514] Thyroid carcinoma[MeSHID:D013964] Hyperthyroidism[MeSHID:D006980] Constipation[MeSHID:D003248] Desiccation[MeSHID:D003890] Pituitary Diseases[MeSHID:D010900] Pallor[MeSHID:D010167] Term Birth[MeSHID:D047929] Hypothyroidism[MeSHID:D007037] Thyroid Gland[MeSHID:D013961] Endemic goiter[MeSHID:D006043] Neoplasm Metastasis[MeSHID:D009362] Hypothalamic structure[MeSHID:D007031] Plasma[MeSHID:D010949] Subacute thyroiditis[MeSHID:D013968] Voice[MeSHID:D014831] Hair[MeSHID:D006197] Lethargy[MeSHID:D053609] Drowsiness[MeSHID:D012894] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Congestive heart failure[MeSHID:D006333] |
0.89 | approved,vet_approved | agonist |
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