| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| levosimendan | atp-sensitive inward rectifier potassium channel 11 | small molecule | NA | drugbank , DGIDB | Heart Diseases[MeSHID:D006331] Congestive heart failure[MeSHID:D006333] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Pulmonary Hypertension[MeSHID:D006976] Cardiac Output[MeSHID:D002302] Heart failure[MeSHID:D006333] Syndrome[MeSHID:D013577] |
2.19 | approved,investigational | inducer |
| levosimendan | atp-sensitive inward rectifier potassium channel 8 | small molecule | NA | drugbank | Heart Diseases[MeSHID:D006331] Congestive heart failure[MeSHID:D006333] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Pulmonary Hypertension[MeSHID:D006976] Cardiac Output[MeSHID:D002302] Heart failure[MeSHID:D006333] Syndrome[MeSHID:D013577] |
NA | approved,investigational | inducer |
| levosimendan | cgmp-inhibited 3',5'-cyclic phosphodiesterase a | small molecule | NA | drugbank | Heart Diseases[MeSHID:D006331] Congestive heart failure[MeSHID:D006333] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Pulmonary Hypertension[MeSHID:D006976] Cardiac Output[MeSHID:D002302] Heart failure[MeSHID:D006333] Syndrome[MeSHID:D013577] |
NA | approved,investigational | inhibitor |
| levosimendan | troponin c, slow skeletal and cardiac muscles | small molecule | NA | drugbank , DGIDB | Heart Diseases[MeSHID:D006331] Congestive heart failure[MeSHID:D006333] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Pulmonary Hypertension[MeSHID:D006976] Cardiac Output[MeSHID:D002302] Heart failure[MeSHID:D006333] Syndrome[MeSHID:D013577] |
57.29 | approved,investigational | potentiator |
| levosimendan | troponin c | NA | Successful target | TTD , DGIDB | Heart Diseases[MeSHID:D006331] Congestive heart failure[MeSHID:D006333] Term Birth[MeSHID:D047929] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Pulmonary Hypertension[MeSHID:D006976] Cardiac Output[MeSHID:D002302] Heart failure[MeSHID:D006333] Syndrome[MeSHID:D013577] |
57.29 | approved | unknown |
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