Drug-Target Information | ||||||||
---|---|---|---|---|---|---|---|---|
Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
lasofoxifene | cannabinoid receptor 2 | small molecule | NA | drugbank | Disease[MeSHID:D004194] Osteoporosis Postmenopausal[MeSHID:D015663] Bone structure of spine[MeSHID:D013131] Vagina[MeSHID:D014621] Fracture[MeSHID:D050723] Malignant neoplasm of breast[MeSHID:D001943] Risk Reduction[MeSHID:D040242] Atrophic[MeSHID:D001284] Vulva[MeSHID:D014844] Virus Diseases[MeSHID:D014777] Osteoporosis[MeSHID:D010024] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inverse agonist |
lasofoxifene | estrogen receptor | NA | Successful target | TTD , DGIDB | Disease[MeSHID:D004194] Osteoporosis Postmenopausal[MeSHID:D015663] Bone structure of spine[MeSHID:D013131] Vagina[MeSHID:D014621] Fracture[MeSHID:D050723] Malignant neoplasm of breast[MeSHID:D001943] Risk Reduction[MeSHID:D040242] Atrophic[MeSHID:D001284] Vulva[MeSHID:D014844] Virus Diseases[MeSHID:D014777] Osteoporosis[MeSHID:D010024] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.63 | approved | agonist |
lasofoxifene | estrogen receptor alpha | small molecule | NA | drugbank , DGIDB | Disease[MeSHID:D004194] Osteoporosis Postmenopausal[MeSHID:D015663] Bone structure of spine[MeSHID:D013131] Vagina[MeSHID:D014621] Fracture[MeSHID:D050723] Malignant neoplasm of breast[MeSHID:D001943] Risk Reduction[MeSHID:D040242] Atrophic[MeSHID:D001284] Vulva[MeSHID:D014844] Virus Diseases[MeSHID:D014777] Osteoporosis[MeSHID:D010024] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.63 | approved,investigational | antagonist,agonist,negative modulator |
lasofoxifene | estrogen receptor | NA | Successful target | TTD , DGIDB | Disease[MeSHID:D004194] Osteoporosis Postmenopausal[MeSHID:D015663] Bone structure of spine[MeSHID:D013131] Vagina[MeSHID:D014621] Fracture[MeSHID:D050723] Malignant neoplasm of breast[MeSHID:D001943] Risk Reduction[MeSHID:D040242] Atrophic[MeSHID:D001284] Vulva[MeSHID:D014844] Virus Diseases[MeSHID:D014777] Osteoporosis[MeSHID:D010024] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.63 | approved | unknown |
lasofoxifene | estrogen receptor beta | small molecule | NA | drugbank , DGIDB | Disease[MeSHID:D004194] Osteoporosis Postmenopausal[MeSHID:D015663] Bone structure of spine[MeSHID:D013131] Vagina[MeSHID:D014621] Fracture[MeSHID:D050723] Malignant neoplasm of breast[MeSHID:D001943] Risk Reduction[MeSHID:D040242] Atrophic[MeSHID:D001284] Vulva[MeSHID:D014844] Virus Diseases[MeSHID:D014777] Osteoporosis[MeSHID:D010024] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.92 | approved,investigational | agonist |
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