Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
larotrectinib high affinity nerve growth factor receptor small molecule NA drugbank , DGIDB Neoplasms[MeSHID:D009369]
Operative Surgical Procedures[MeSHID:D013514]
Mutation[MeSHID:D009154]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Malignant Neoplasms[MeSHID:D009369]		 3.07 approved,investigational inhibitor
larotrectinib tropomyosin-related kinase a NA Successful target TTD , DGIDB Neoplasms[MeSHID:D009369]
Operative Surgical Procedures[MeSHID:D013514]
Mutation[MeSHID:D009154]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Malignant Neoplasms[MeSHID:D009369]		 3.07 approved inhibitor
larotrectinib tropomyosin-related kinase a NA Successful target TTD , DGIDB Neoplasms[MeSHID:D009369]
Operative Surgical Procedures[MeSHID:D013514]
Mutation[MeSHID:D009154]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Malignant Neoplasms[MeSHID:D009369]		 3.07 approved unknown
larotrectinib bdnf/nt-3 growth factors receptor small molecule Successful target TTD , drugbank , DGIDB Neoplasms[MeSHID:D009369]
Operative Surgical Procedures[MeSHID:D013514]
Mutation[MeSHID:D009154]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Malignant Neoplasms[MeSHID:D009369]		 2.48 approved,investigational inhibitor
larotrectinib nt-3 growth factor receptor small molecule Successful target TTD , drugbank , DGIDB Neoplasms[MeSHID:D009369]
Operative Surgical Procedures[MeSHID:D013514]
Mutation[MeSHID:D009154]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Malignant Neoplasms[MeSHID:D009369]		 5.62 approved,investigational inhibitor
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