| Drug-Target Information | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
| lamotrigine | adenosine receptor a1 | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | adenosine receptor a2a | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | alpha-1a adrenergic receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | alpha-2a adrenergic receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | beta-1 adrenergic receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | voltage-dependent r-type calcium channel subunit alpha-1e (cacna1e) | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | acetylcholine receptor subunit alpha | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | d(1) dopamine receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | dopamine d2 receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | agonist,inhibitor |
| lamotrigine | d(1) dopamine receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | gaba(a) receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist,inducer |
| lamotrigine | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | gaba(a) receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist,inducer |
| lamotrigine | gaba(a) receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist,inducer |
| lamotrigine | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | gaba(a) receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist,inducer |
| lamotrigine | gaba(a) receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist,inducer |
| lamotrigine | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | gaba(a) receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist,inducer |
| lamotrigine | gaba(a) receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist,inducer |
| lamotrigine | gaba(a) receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist,inducer |
| lamotrigine | gaba(a) receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist,inducer |
| lamotrigine | gaba(a) receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist,inducer |
| lamotrigine | gaba(a) receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist,inducer |
| lamotrigine | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | gaba(a) receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist,inducer |
| lamotrigine | gaba(a) receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist,inducer |
| lamotrigine | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | gaba(a) receptor benzodiazepine binding site | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | gaba(a) receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist,inducer |
| lamotrigine | gaba(a) receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist,inducer |
| lamotrigine | gaba(a) receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist,inducer |
| lamotrigine | glutamate receptor 1 | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | histamine h1 receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | antagonist |
| lamotrigine | 5-hydroxytryptamine receptor 2a | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | 5-hydroxytryptamine receptor 3a | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | kappa-type opioid receptor | small molecule | NA | drugbank | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
| lamotrigine | voltage-gated sodium channel alpha subunit | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.03 | approved,investigational | inhibitor,blocker |
| lamotrigine | voltage-gated sodium channel alpha subunit | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.08 | approved,investigational | inhibitor |
| lamotrigine | voltage-gated sodium channel alpha nav1.9 | NA | Successful target | TTD , DGIDB | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.08 | approved | unknown |
| lamotrigine | voltage-gated sodium channel alpha nav1.9 | NA | Successful target | TTD , DGIDB | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.08 | approved | blocker |
| lamotrigine | voltage-gated sodium channel alpha subunit | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.08 | approved,investigational | inhibitor,blocker |
| lamotrigine | voltage-gated sodium channel alpha subunit | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.28 | approved,investigational | inhibitor |
| lamotrigine | voltage-gated sodium channel alpha subunit | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.28 | approved,investigational | inhibitor,blocker |
| lamotrigine | voltage-gated sodium channel alpha subunit | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.33 | approved,investigational | inhibitor |
| lamotrigine | voltage-gated sodium channel alpha subunit | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.33 | approved,investigational | inhibitor,blocker |
| lamotrigine | voltage-gated sodium channel alpha subunit | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.04 | approved,investigational | inhibitor,blocker |
| lamotrigine | voltage-gated sodium channel alpha subunit | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.04 | approved,investigational | inhibitor,blocker |
| lamotrigine | voltage-gated sodium channel alpha subunit | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.03 | approved,investigational | inhibitor,blocker |
| lamotrigine | voltage-gated sodium channel alpha subunit | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.04 | approved,investigational | inhibitor,blocker |
| lamotrigine | voltage-gated sodium channel alpha subunit | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.04 | approved,investigational | inhibitor,blocker |
| lamotrigine | voltage-gated sodium channel alpha subunit | small molecule | NA | drugbank , DGIDB | Bipolar Disorder[MeSHID:D001714] Depressive disorder[MeSHID:D003866] Maintenance[MeSHID:D008283] Mood (psychological function)[MeSHID:D000339] Epilepsy[MeSHID:D004827] Mental Depression[MeSHID:D003863] Unmarried[MeSHID:D012847] Seizures Focal[MeSHID:D012640] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.04 | approved,investigational | inhibitor,blocker |
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