Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
irinotecan dna topoisomerase 1 small molecule NA drugbank , DGIDB Adenocarcinoma[MeSHID:D000230]
Pancreas[MeSHID:D010179]
Colorectal Cancer[MeSHID:D015179]
Neoplasm Metastasis[MeSHID:D009362]
Small cell carcinoma of lung[MeSHID:D055752]
Disease Progression[MeSHID:D018450]
Recurrence (disease attribute)[MeSHID:D012008]
cervical cancer[MeSHID:D002583]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.28 approved,investigational inhibitor
irinotecan dna topoisomerase i NA Successful target TTD , DGIDB Adenocarcinoma[MeSHID:D000230]
Pancreas[MeSHID:D010179]
Colorectal Cancer[MeSHID:D015179]
Neoplasm Metastasis[MeSHID:D009362]
Small cell carcinoma of lung[MeSHID:D055752]
Disease Progression[MeSHID:D018450]
Recurrence (disease attribute)[MeSHID:D012008]
cervical cancer[MeSHID:D002583]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.28 approved inhibitor
irinotecan dna topoisomerase i NA Successful target TTD , DGIDB Adenocarcinoma[MeSHID:D000230]
Pancreas[MeSHID:D010179]
Colorectal Cancer[MeSHID:D015179]
Neoplasm Metastasis[MeSHID:D009362]
Small cell carcinoma of lung[MeSHID:D055752]
Disease Progression[MeSHID:D018450]
Recurrence (disease attribute)[MeSHID:D012008]
cervical cancer[MeSHID:D002583]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.28 approved unknown
irinotecan dna topoisomerase i, mitochondrial small molecule NA drugbank , DGIDB Adenocarcinoma[MeSHID:D000230]
Pancreas[MeSHID:D010179]
Colorectal Cancer[MeSHID:D015179]
Neoplasm Metastasis[MeSHID:D009362]
Small cell carcinoma of lung[MeSHID:D055752]
Disease Progression[MeSHID:D018450]
Recurrence (disease attribute)[MeSHID:D012008]
cervical cancer[MeSHID:D002583]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 4.4 approved,investigational inhibitor
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