Drug-Target Information | ||||||||
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Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
indomethacin | aldo-keto reductase family 1 member c3 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Disease[MeSHID:D004194] |
0.5 | approved,investigational | inhibitor |
indomethacin | aldo-keto reductase family 1 member c3 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.5 | approved,investigational | inhibitor |
indomethacin | interferon-induced, double-stranded rna-activated protein kinase | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inducer |
indomethacin | interferon-induced, double-stranded rna-activated protein kinase | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Disease[MeSHID:D004194] |
NA | approved,investigational | inducer |
indomethacin | lactoylglutathione lyase | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Disease[MeSHID:D004194] |
NA | approved,investigational | inhibitor |
indomethacin | lactoylglutathione lyase | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
indomethacin | phospholipase a2, membrane associated | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Disease[MeSHID:D004194] |
NA | approved,investigational | inhibitor |
indomethacin | phospholipase a2, membrane associated | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
indomethacin | peroxisome proliferator-activated receptor alpha | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Disease[MeSHID:D004194] |
NA | approved,investigational | agonist |
indomethacin | peroxisome proliferator-activated receptor alpha | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | agonist |
indomethacin | peroxisome proliferator-activated receptor gamma | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.04 | approved,investigational | activator,agonist |
indomethacin | peroxisome proliferator-activated receptor gamma | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Disease[MeSHID:D004194] |
0.04 | approved,investigational | activator,agonist |
indomethacin | prostaglandin d2 receptor 2 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Disease[MeSHID:D004194] |
0.37 | approved,investigational | agonist |
indomethacin | prostaglandin d2 receptor 2 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.37 | approved,investigational | agonist |
indomethacin | prostaglandin reductase 2 | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
NA | approved,investigational | inhibitor |
indomethacin | prostaglandin reductase 2 | small molecule | NA | drugbank | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Disease[MeSHID:D004194] |
NA | approved,investigational | inhibitor |
indomethacin | prostaglandin g/h synthase 1 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.33 | approved,investigational | inhibitor |
indomethacin | prostaglandin g/h synthase 1 | small molecule | NA | drugbank , DGIDB | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Disease[MeSHID:D004194] |
0.33 | approved,investigational | inhibitor |
indomethacin | prostaglandin g/h synthase 2 | small molecule | Successful target | TTD , drugbank , DGIDB | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Coronavirus Infections[MeSHID:D018352] Disease[MeSHID:D004194] |
0.3 | approved,investigational | inhibitor |
indomethacin | prostaglandin g/h synthase 2 | small molecule | Successful target | TTD , drugbank , DGIDB | Disease Management[MeSHID:D019468] Acute onset pain[MeSHID:D059787] Patent ductus arteriosus[MeSHID:D004374] Degenerative polyarthritis[MeSHID:D010003] Tendinitis[MeSHID:D052256] Ankylosing spondylitis[MeSHID:D013167] Rheumatoid Arthritis[MeSHID:D001172] Arthritis Gouty[MeSHID:D015210] Bursitis[MeSHID:D002062] Body Fluids[MeSHID:D001826] Chronic disease[MeSHID:D002908] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] |
0.3 | approved,investigational | inhibitor |
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