Drug-Target Information | ||||||||
---|---|---|---|---|---|---|---|---|
Drug Name | Target Name | Drug Type | Target Type | Source | Drug MeSHID | Interaction Score | Drug Status | Target Action |
imatinib | tyrosine-protein kinase abl1 | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disease[MeSHID:D004194] Middle East Respiratory Syndrome[MeSHID:D018352] |
0.51 | approved | inhibitor |
imatinib | tyrosine-protein kinase abl1 | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of lung[MeSHID:D008175] Intestinal Cancer[MeSHID:D007414] Mastocytosis Systemic[MeSHID:D034721] |
0.51 | approved | inhibitor |
imatinib | breakpoint cluster region protein | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of lung[MeSHID:D008175] Intestinal Cancer[MeSHID:D007414] Mastocytosis Systemic[MeSHID:D034721] |
0.83 | approved | inhibitor |
imatinib | breakpoint cluster region protein | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disease[MeSHID:D004194] Middle East Respiratory Syndrome[MeSHID:D018352] |
0.83 | approved | inhibitor |
imatinib | macrophage colony-stimulating factor 1 receptor | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disease[MeSHID:D004194] Middle East Respiratory Syndrome[MeSHID:D018352] |
0.22 | approved | antagonist |
imatinib | macrophage colony-stimulating factor 1 receptor | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of lung[MeSHID:D008175] Intestinal Cancer[MeSHID:D007414] Mastocytosis Systemic[MeSHID:D034721] |
0.22 | approved | antagonist |
imatinib | epithelial discoidin domain-containing receptor 1 | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disease[MeSHID:D004194] Middle East Respiratory Syndrome[MeSHID:D018352] |
2.65 | approved | antagonist,inhibitor |
imatinib | epithelial discoidin domain-containing receptor 1 | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of lung[MeSHID:D008175] Intestinal Cancer[MeSHID:D007414] Mastocytosis Systemic[MeSHID:D034721] |
2.65 | approved | antagonist |
imatinib | epithelial discoidin domain-containing receptor 1 | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of lung[MeSHID:D008175] Intestinal Cancer[MeSHID:D007414] Mastocytosis Systemic[MeSHID:D034721] |
2.65 | approved | antagonist,inhibitor |
imatinib | epithelial discoidin domain-containing receptor 1 | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disease[MeSHID:D004194] Middle East Respiratory Syndrome[MeSHID:D018352] |
2.65 | approved | antagonist |
imatinib | mast/stem cell growth factor receptor kit | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disease[MeSHID:D004194] Middle East Respiratory Syndrome[MeSHID:D018352] |
1.35 | approved | antagonist,inhibitor |
imatinib | tyrosine-protein kinase kit | NA | Successful target | TTD , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disease[MeSHID:D004194] Middle East Respiratory Syndrome[MeSHID:D018352] |
1.35 | approved | unknown |
imatinib | tyrosine-protein kinase kit | NA | Successful target | TTD , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of lung[MeSHID:D008175] Intestinal Cancer[MeSHID:D007414] Mastocytosis Systemic[MeSHID:D034721] |
1.35 | approved | unknown |
imatinib | tyrosine-protein kinase kit | NA | Successful target | TTD , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disease[MeSHID:D004194] Middle East Respiratory Syndrome[MeSHID:D018352] |
1.35 | approved | inhibitor |
imatinib | mast/stem cell growth factor receptor kit | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of lung[MeSHID:D008175] Intestinal Cancer[MeSHID:D007414] Mastocytosis Systemic[MeSHID:D034721] |
1.35 | approved | antagonist,inhibitor |
imatinib | mast/stem cell growth factor receptor kit | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of lung[MeSHID:D008175] Intestinal Cancer[MeSHID:D007414] Mastocytosis Systemic[MeSHID:D034721] |
1.35 | approved | antagonist |
imatinib | mast/stem cell growth factor receptor kit | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disease[MeSHID:D004194] Middle East Respiratory Syndrome[MeSHID:D018352] |
1.35 | approved | antagonist |
imatinib | tyrosine-protein kinase kit | NA | Successful target | TTD , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of lung[MeSHID:D008175] Intestinal Cancer[MeSHID:D007414] Mastocytosis Systemic[MeSHID:D034721] |
1.35 | approved | inhibitor |
imatinib | mcl-1 messenger rna | NA | Successful target | TTD | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of lung[MeSHID:D008175] Intestinal Cancer[MeSHID:D007414] Mastocytosis Systemic[MeSHID:D034721] |
NA | approved | unknown |
imatinib | mcl-1 messenger rna | NA | Successful target | TTD | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disease[MeSHID:D004194] Middle East Respiratory Syndrome[MeSHID:D018352] |
NA | approved | unknown |
imatinib | high affinity nerve growth factor receptor | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disease[MeSHID:D004194] Middle East Respiratory Syndrome[MeSHID:D018352] |
0.12 | approved | antagonist |
imatinib | high affinity nerve growth factor receptor | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of lung[MeSHID:D008175] Intestinal Cancer[MeSHID:D007414] Mastocytosis Systemic[MeSHID:D034721] |
0.12 | approved | antagonist |
imatinib | platelet-derived growth factor receptor alpha | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of lung[MeSHID:D008175] Intestinal Cancer[MeSHID:D007414] Mastocytosis Systemic[MeSHID:D034721] |
0.59 | approved | antagonist,inhibitor |
imatinib | platelet-derived growth factor receptor alpha | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disease[MeSHID:D004194] Middle East Respiratory Syndrome[MeSHID:D018352] |
0.59 | approved | antagonist,inhibitor |
imatinib | platelet-derived growth factor receptor alpha | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disease[MeSHID:D004194] Middle East Respiratory Syndrome[MeSHID:D018352] |
0.59 | approved | antagonist |
imatinib | platelet-derived growth factor receptor alpha | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of lung[MeSHID:D008175] Intestinal Cancer[MeSHID:D007414] Mastocytosis Systemic[MeSHID:D034721] |
0.59 | approved | antagonist |
imatinib | platelet-derived growth factor receptor beta | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disease[MeSHID:D004194] Middle East Respiratory Syndrome[MeSHID:D018352] |
0.23 | approved | antagonist,inhibitor |
imatinib | platelet-derived growth factor receptor beta | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disease[MeSHID:D004194] Middle East Respiratory Syndrome[MeSHID:D018352] |
0.23 | approved | antagonist |
imatinib | platelet-derived growth factor receptor beta | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of lung[MeSHID:D008175] Intestinal Cancer[MeSHID:D007414] Mastocytosis Systemic[MeSHID:D034721] |
0.23 | approved | antagonist |
imatinib | platelet-derived growth factor receptor beta | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of lung[MeSHID:D008175] Intestinal Cancer[MeSHID:D007414] Mastocytosis Systemic[MeSHID:D034721] |
0.23 | approved | antagonist,inhibitor |
imatinib | ret proto-oncogene | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Malignant neoplasm of lung[MeSHID:D008175] Intestinal Cancer[MeSHID:D007414] Mastocytosis Systemic[MeSHID:D034721] |
0.04 | approved | inhibitor |
imatinib | ret proto-oncogene | small molecule | NA | drugbank , DGIDB | Aggressive Systemic Mastocytosis[MeSHID:D034721] Myelodysplastic-Myeloproliferative Diseases[MeSHID:D054437] Pdgfra-Associated Chronic Eosinophilic Leukemia[MeSHID:C580364] Dermatofibrosarcoma[MeSHID:D018223] Gastrointestinal Stromal Tumors[MeSHID:D046152] Precursor Cell Lymphoblastic Leukemia Lymphoma[MeSHID:D054198] PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA[MeSHID:C564650] Hypereosinophilic syndrome[MeSHID:D017681] Chromosomes[MeSHID:D002875] Myeloid Leukemia Chronic[MeSHID:D015464] Disruptive Impulse Control and Conduct Disorders[MeSHID:D007174] Severe Acute Respiratory Syndrome[MeSHID:D045169] Disease[MeSHID:D004194] Middle East Respiratory Syndrome[MeSHID:D018352] |
0.04 | approved | inhibitor |
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