Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
iloperidone alpha-1a adrenergic receptor small molecule NA drugbank , DGIDB Schizophrenia[MeSHID:D012559]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.08 approved antagonist
iloperidone alpha-2c adrenergic receptor small molecule NA drugbank , DGIDB Schizophrenia[MeSHID:D012559]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.05 approved antagonist
iloperidone dopamine d1 receptor small molecule NA drugbank , DGIDB Schizophrenia[MeSHID:D012559]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.05 approved antagonist
iloperidone dopamine d2 receptor small molecule Successful target TTD , drugbank , DGIDB Schizophrenia[MeSHID:D012559]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.14 approved antagonist
iloperidone dopamine d3 receptor small molecule NA drugbank , DGIDB Schizophrenia[MeSHID:D012559]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.1 approved antagonist
iloperidone dopamine d4 receptor small molecule NA drugbank Schizophrenia[MeSHID:D012559]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved antagonist
iloperidone histamine h1 receptor small molecule NA drugbank , DGIDB Schizophrenia[MeSHID:D012559]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.05 approved antagonist
iloperidone 5-hydroxytryptamine receptor 1a small molecule NA drugbank , DGIDB Schizophrenia[MeSHID:D012559]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.12 approved antagonist
iloperidone 5-ht 2a receptor NA Successful target TTD , DGIDB Schizophrenia[MeSHID:D012559]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.15 approved antagonist
iloperidone 5-hydroxytryptamine receptor 2a small molecule NA drugbank , DGIDB Schizophrenia[MeSHID:D012559]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.15 approved antagonist
iloperidone 5-ht 2a receptor NA Successful target TTD , DGIDB Schizophrenia[MeSHID:D012559]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.15 approved unknown
iloperidone 5-hydroxytryptamine receptor 6 small molecule NA drugbank , DGIDB Schizophrenia[MeSHID:D012559]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.3 approved antagonist
iloperidone 5-hydroxytryptamine receptor 7 small molecule NA drugbank , DGIDB Schizophrenia[MeSHID:D012559]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.27 approved antagonist
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