Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
ibuprofen apoptosis regulator bcl-2 small molecule NA drugbank Diuretic Effect[MeSHID:D004232]
Cystic Fibrosis[MeSHID:D003550]
Pregnancy
Prolonged[MeSHID:D011273]
Pain[MeSHID:D010146]
Platelet aggregation[MeSHID:D010974]
Psychological inhibition[MeSHID:D007266]
Pain
Postoperative[MeSHID:D010149]
Body tissue[MeSHID:D014024]
Rheumatoid Arthritis[MeSHID:D001172]
Tension Headache[MeSHID:D018781]
Fever[MeSHID:D005334]
Malignant neoplasm of breast[MeSHID:D001943]
Hypotension
Orthostatic[MeSHID:D007024]
Migraine Disorders[MeSHID:D008881]
Degenerative polyarthritis[MeSHID:D010003]
Patent ductus arteriosus[MeSHID:D004374]
Dental Health Services[MeSHID:D003752]
Heart failure[MeSHID:D006333]
Lung[MeSHID:D008168]
Inflammation[MeSHID:D007249]
Parkinson Disease[MeSHID:D010300]
Descending aorta[MeSHID:D001013]
Arthritis[MeSHID:D001168]
Dysmenorrhea[MeSHID:D004412]
Chronic pain[MeSHID:D059350]
Blood Vessel[MeSHID:D001808]
Disease[MeSHID:D004194]
Headache[MeSHID:D006261]
Labor (Childbirth)[MeSHID:D007743]
Pulmonary artery structure[MeSHID:D011651]
Hypernatremia[MeSHID:D006955]
Rheumatism[MeSHID:D012216]
Toothache[MeSHID:D014098]
Birth[MeSHID:D036801]
Spondylitis[MeSHID:D013166]
neutrophil[MeSHID:D009504]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved modulator
ibuprofen cystic fibrosis transmembrane conductance regulator small molecule NA drugbank Diuretic Effect[MeSHID:D004232]
Cystic Fibrosis[MeSHID:D003550]
Pregnancy
Prolonged[MeSHID:D011273]
Pain[MeSHID:D010146]
Platelet aggregation[MeSHID:D010974]
Psychological inhibition[MeSHID:D007266]
Pain
Postoperative[MeSHID:D010149]
Body tissue[MeSHID:D014024]
Rheumatoid Arthritis[MeSHID:D001172]
Tension Headache[MeSHID:D018781]
Fever[MeSHID:D005334]
Malignant neoplasm of breast[MeSHID:D001943]
Hypotension
Orthostatic[MeSHID:D007024]
Migraine Disorders[MeSHID:D008881]
Degenerative polyarthritis[MeSHID:D010003]
Patent ductus arteriosus[MeSHID:D004374]
Dental Health Services[MeSHID:D003752]
Heart failure[MeSHID:D006333]
Lung[MeSHID:D008168]
Inflammation[MeSHID:D007249]
Parkinson Disease[MeSHID:D010300]
Descending aorta[MeSHID:D001013]
Arthritis[MeSHID:D001168]
Dysmenorrhea[MeSHID:D004412]
Chronic pain[MeSHID:D059350]
Blood Vessel[MeSHID:D001808]
Disease[MeSHID:D004194]
Headache[MeSHID:D006261]
Labor (Childbirth)[MeSHID:D007743]
Pulmonary artery structure[MeSHID:D011651]
Hypernatremia[MeSHID:D006955]
Rheumatism[MeSHID:D012216]
Toothache[MeSHID:D014098]
Birth[MeSHID:D036801]
Spondylitis[MeSHID:D013166]
neutrophil[MeSHID:D009504]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved inhibitor
ibuprofen interleukin-8 NA Successful target TTD , DGIDB Diuretic Effect[MeSHID:D004232]
Cystic Fibrosis[MeSHID:D003550]
Pregnancy
Prolonged[MeSHID:D011273]
Pain[MeSHID:D010146]
Platelet aggregation[MeSHID:D010974]
Psychological inhibition[MeSHID:D007266]
Pain
Postoperative[MeSHID:D010149]
Body tissue[MeSHID:D014024]
Rheumatoid Arthritis[MeSHID:D001172]
Tension Headache[MeSHID:D018781]
Fever[MeSHID:D005334]
Malignant neoplasm of breast[MeSHID:D001943]
Hypotension
Orthostatic[MeSHID:D007024]
Migraine Disorders[MeSHID:D008881]
Degenerative polyarthritis[MeSHID:D010003]
Patent ductus arteriosus[MeSHID:D004374]
Dental Health Services[MeSHID:D003752]
Heart failure[MeSHID:D006333]
Lung[MeSHID:D008168]
Inflammation[MeSHID:D007249]
Parkinson Disease[MeSHID:D010300]
Descending aorta[MeSHID:D001013]
Arthritis[MeSHID:D001168]
Dysmenorrhea[MeSHID:D004412]
Chronic pain[MeSHID:D059350]
Blood Vessel[MeSHID:D001808]
Disease[MeSHID:D004194]
Headache[MeSHID:D006261]
Labor (Childbirth)[MeSHID:D007743]
Pulmonary artery structure[MeSHID:D011651]
Hypernatremia[MeSHID:D006955]
Rheumatism[MeSHID:D012216]
Toothache[MeSHID:D014098]
Birth[MeSHID:D036801]
Spondylitis[MeSHID:D013166]
neutrophil[MeSHID:D009504]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.03 approved unknown
ibuprofen c-x-c chemokine receptor type 1 NA Successful target TTD , DGIDB Diuretic Effect[MeSHID:D004232]
Cystic Fibrosis[MeSHID:D003550]
Pregnancy
Prolonged[MeSHID:D011273]
Pain[MeSHID:D010146]
Platelet aggregation[MeSHID:D010974]
Psychological inhibition[MeSHID:D007266]
Pain
Postoperative[MeSHID:D010149]
Body tissue[MeSHID:D014024]
Rheumatoid Arthritis[MeSHID:D001172]
Tension Headache[MeSHID:D018781]
Fever[MeSHID:D005334]
Malignant neoplasm of breast[MeSHID:D001943]
Hypotension
Orthostatic[MeSHID:D007024]
Migraine Disorders[MeSHID:D008881]
Degenerative polyarthritis[MeSHID:D010003]
Patent ductus arteriosus[MeSHID:D004374]
Dental Health Services[MeSHID:D003752]
Heart failure[MeSHID:D006333]
Lung[MeSHID:D008168]
Inflammation[MeSHID:D007249]
Parkinson Disease[MeSHID:D010300]
Descending aorta[MeSHID:D001013]
Arthritis[MeSHID:D001168]
Dysmenorrhea[MeSHID:D004412]
Chronic pain[MeSHID:D059350]
Blood Vessel[MeSHID:D001808]
Disease[MeSHID:D004194]
Headache[MeSHID:D006261]
Labor (Childbirth)[MeSHID:D007743]
Pulmonary artery structure[MeSHID:D011651]
Hypernatremia[MeSHID:D006955]
Rheumatism[MeSHID:D012216]
Toothache[MeSHID:D014098]
Birth[MeSHID:D036801]
Spondylitis[MeSHID:D013166]
neutrophil[MeSHID:D009504]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.37 approved unknown
ibuprofen c-x-c chemokine receptor type 2 NA Successful target TTD , DGIDB Diuretic Effect[MeSHID:D004232]
Cystic Fibrosis[MeSHID:D003550]
Pregnancy
Prolonged[MeSHID:D011273]
Pain[MeSHID:D010146]
Platelet aggregation[MeSHID:D010974]
Psychological inhibition[MeSHID:D007266]
Pain
Postoperative[MeSHID:D010149]
Body tissue[MeSHID:D014024]
Rheumatoid Arthritis[MeSHID:D001172]
Tension Headache[MeSHID:D018781]
Fever[MeSHID:D005334]
Malignant neoplasm of breast[MeSHID:D001943]
Hypotension
Orthostatic[MeSHID:D007024]
Migraine Disorders[MeSHID:D008881]
Degenerative polyarthritis[MeSHID:D010003]
Patent ductus arteriosus[MeSHID:D004374]
Dental Health Services[MeSHID:D003752]
Heart failure[MeSHID:D006333]
Lung[MeSHID:D008168]
Inflammation[MeSHID:D007249]
Parkinson Disease[MeSHID:D010300]
Descending aorta[MeSHID:D001013]
Arthritis[MeSHID:D001168]
Dysmenorrhea[MeSHID:D004412]
Chronic pain[MeSHID:D059350]
Blood Vessel[MeSHID:D001808]
Disease[MeSHID:D004194]
Headache[MeSHID:D006261]
Labor (Childbirth)[MeSHID:D007743]
Pulmonary artery structure[MeSHID:D011651]
Hypernatremia[MeSHID:D006955]
Rheumatism[MeSHID:D012216]
Toothache[MeSHID:D014098]
Birth[MeSHID:D036801]
Spondylitis[MeSHID:D013166]
neutrophil[MeSHID:D009504]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.17 approved unknown
ibuprofen fatty acid-binding protein, intestinal small molecule NA drugbank Diuretic Effect[MeSHID:D004232]
Cystic Fibrosis[MeSHID:D003550]
Pregnancy
Prolonged[MeSHID:D011273]
Pain[MeSHID:D010146]
Platelet aggregation[MeSHID:D010974]
Psychological inhibition[MeSHID:D007266]
Pain
Postoperative[MeSHID:D010149]
Body tissue[MeSHID:D014024]
Rheumatoid Arthritis[MeSHID:D001172]
Tension Headache[MeSHID:D018781]
Fever[MeSHID:D005334]
Malignant neoplasm of breast[MeSHID:D001943]
Hypotension
Orthostatic[MeSHID:D007024]
Migraine Disorders[MeSHID:D008881]
Degenerative polyarthritis[MeSHID:D010003]
Patent ductus arteriosus[MeSHID:D004374]
Dental Health Services[MeSHID:D003752]
Heart failure[MeSHID:D006333]
Lung[MeSHID:D008168]
Inflammation[MeSHID:D007249]
Parkinson Disease[MeSHID:D010300]
Descending aorta[MeSHID:D001013]
Arthritis[MeSHID:D001168]
Dysmenorrhea[MeSHID:D004412]
Chronic pain[MeSHID:D059350]
Blood Vessel[MeSHID:D001808]
Disease[MeSHID:D004194]
Headache[MeSHID:D006261]
Labor (Childbirth)[MeSHID:D007743]
Pulmonary artery structure[MeSHID:D011651]
Hypernatremia[MeSHID:D006955]
Rheumatism[MeSHID:D012216]
Toothache[MeSHID:D014098]
Birth[MeSHID:D036801]
Spondylitis[MeSHID:D013166]
neutrophil[MeSHID:D009504]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved binder
ibuprofen platelet glycoprotein ib alpha chain small molecule NA drugbank Diuretic Effect[MeSHID:D004232]
Cystic Fibrosis[MeSHID:D003550]
Pregnancy
Prolonged[MeSHID:D011273]
Pain[MeSHID:D010146]
Platelet aggregation[MeSHID:D010974]
Psychological inhibition[MeSHID:D007266]
Pain
Postoperative[MeSHID:D010149]
Body tissue[MeSHID:D014024]
Rheumatoid Arthritis[MeSHID:D001172]
Tension Headache[MeSHID:D018781]
Fever[MeSHID:D005334]
Malignant neoplasm of breast[MeSHID:D001943]
Hypotension
Orthostatic[MeSHID:D007024]
Migraine Disorders[MeSHID:D008881]
Degenerative polyarthritis[MeSHID:D010003]
Patent ductus arteriosus[MeSHID:D004374]
Dental Health Services[MeSHID:D003752]
Heart failure[MeSHID:D006333]
Lung[MeSHID:D008168]
Inflammation[MeSHID:D007249]
Parkinson Disease[MeSHID:D010300]
Descending aorta[MeSHID:D001013]
Arthritis[MeSHID:D001168]
Dysmenorrhea[MeSHID:D004412]
Chronic pain[MeSHID:D059350]
Blood Vessel[MeSHID:D001808]
Disease[MeSHID:D004194]
Headache[MeSHID:D006261]
Labor (Childbirth)[MeSHID:D007743]
Pulmonary artery structure[MeSHID:D011651]
Hypernatremia[MeSHID:D006955]
Rheumatism[MeSHID:D012216]
Toothache[MeSHID:D014098]
Birth[MeSHID:D036801]
Spondylitis[MeSHID:D013166]
neutrophil[MeSHID:D009504]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved inducer
ibuprofen peroxisome proliferator-activated receptor alpha small molecule NA drugbank Diuretic Effect[MeSHID:D004232]
Cystic Fibrosis[MeSHID:D003550]
Pregnancy
Prolonged[MeSHID:D011273]
Pain[MeSHID:D010146]
Platelet aggregation[MeSHID:D010974]
Psychological inhibition[MeSHID:D007266]
Pain
Postoperative[MeSHID:D010149]
Body tissue[MeSHID:D014024]
Rheumatoid Arthritis[MeSHID:D001172]
Tension Headache[MeSHID:D018781]
Fever[MeSHID:D005334]
Malignant neoplasm of breast[MeSHID:D001943]
Hypotension
Orthostatic[MeSHID:D007024]
Migraine Disorders[MeSHID:D008881]
Degenerative polyarthritis[MeSHID:D010003]
Patent ductus arteriosus[MeSHID:D004374]
Dental Health Services[MeSHID:D003752]
Heart failure[MeSHID:D006333]
Lung[MeSHID:D008168]
Inflammation[MeSHID:D007249]
Parkinson Disease[MeSHID:D010300]
Descending aorta[MeSHID:D001013]
Arthritis[MeSHID:D001168]
Dysmenorrhea[MeSHID:D004412]
Chronic pain[MeSHID:D059350]
Blood Vessel[MeSHID:D001808]
Disease[MeSHID:D004194]
Headache[MeSHID:D006261]
Labor (Childbirth)[MeSHID:D007743]
Pulmonary artery structure[MeSHID:D011651]
Hypernatremia[MeSHID:D006955]
Rheumatism[MeSHID:D012216]
Toothache[MeSHID:D014098]
Birth[MeSHID:D036801]
Spondylitis[MeSHID:D013166]
neutrophil[MeSHID:D009504]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved activator
ibuprofen peroxisome proliferator-activated receptor gamma small molecule NA drugbank Diuretic Effect[MeSHID:D004232]
Cystic Fibrosis[MeSHID:D003550]
Pregnancy
Prolonged[MeSHID:D011273]
Pain[MeSHID:D010146]
Platelet aggregation[MeSHID:D010974]
Psychological inhibition[MeSHID:D007266]
Pain
Postoperative[MeSHID:D010149]
Body tissue[MeSHID:D014024]
Rheumatoid Arthritis[MeSHID:D001172]
Tension Headache[MeSHID:D018781]
Fever[MeSHID:D005334]
Malignant neoplasm of breast[MeSHID:D001943]
Hypotension
Orthostatic[MeSHID:D007024]
Migraine Disorders[MeSHID:D008881]
Degenerative polyarthritis[MeSHID:D010003]
Patent ductus arteriosus[MeSHID:D004374]
Dental Health Services[MeSHID:D003752]
Heart failure[MeSHID:D006333]
Lung[MeSHID:D008168]
Inflammation[MeSHID:D007249]
Parkinson Disease[MeSHID:D010300]
Descending aorta[MeSHID:D001013]
Arthritis[MeSHID:D001168]
Dysmenorrhea[MeSHID:D004412]
Chronic pain[MeSHID:D059350]
Blood Vessel[MeSHID:D001808]
Disease[MeSHID:D004194]
Headache[MeSHID:D006261]
Labor (Childbirth)[MeSHID:D007743]
Pulmonary artery structure[MeSHID:D011651]
Hypernatremia[MeSHID:D006955]
Rheumatism[MeSHID:D012216]
Toothache[MeSHID:D014098]
Birth[MeSHID:D036801]
Spondylitis[MeSHID:D013166]
neutrophil[MeSHID:D009504]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved activator
ibuprofen prostaglandin g/h synthase 1 small molecule NA drugbank , DGIDB Diuretic Effect[MeSHID:D004232]
Cystic Fibrosis[MeSHID:D003550]
Pregnancy
Prolonged[MeSHID:D011273]
Pain[MeSHID:D010146]
Platelet aggregation[MeSHID:D010974]
Psychological inhibition[MeSHID:D007266]
Pain
Postoperative[MeSHID:D010149]
Body tissue[MeSHID:D014024]
Rheumatoid Arthritis[MeSHID:D001172]
Tension Headache[MeSHID:D018781]
Fever[MeSHID:D005334]
Malignant neoplasm of breast[MeSHID:D001943]
Hypotension
Orthostatic[MeSHID:D007024]
Migraine Disorders[MeSHID:D008881]
Degenerative polyarthritis[MeSHID:D010003]
Patent ductus arteriosus[MeSHID:D004374]
Dental Health Services[MeSHID:D003752]
Heart failure[MeSHID:D006333]
Lung[MeSHID:D008168]
Inflammation[MeSHID:D007249]
Parkinson Disease[MeSHID:D010300]
Descending aorta[MeSHID:D001013]
Arthritis[MeSHID:D001168]
Dysmenorrhea[MeSHID:D004412]
Chronic pain[MeSHID:D059350]
Blood Vessel[MeSHID:D001808]
Disease[MeSHID:D004194]
Headache[MeSHID:D006261]
Labor (Childbirth)[MeSHID:D007743]
Pulmonary artery structure[MeSHID:D011651]
Hypernatremia[MeSHID:D006955]
Rheumatism[MeSHID:D012216]
Toothache[MeSHID:D014098]
Birth[MeSHID:D036801]
Spondylitis[MeSHID:D013166]
neutrophil[MeSHID:D009504]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.43 approved inhibitor
ibuprofen prostaglandin g/h synthase 2 small molecule Successful target TTD , drugbank , DGIDB Diuretic Effect[MeSHID:D004232]
Cystic Fibrosis[MeSHID:D003550]
Pregnancy
Prolonged[MeSHID:D011273]
Pain[MeSHID:D010146]
Platelet aggregation[MeSHID:D010974]
Psychological inhibition[MeSHID:D007266]
Pain
Postoperative[MeSHID:D010149]
Body tissue[MeSHID:D014024]
Rheumatoid Arthritis[MeSHID:D001172]
Tension Headache[MeSHID:D018781]
Fever[MeSHID:D005334]
Malignant neoplasm of breast[MeSHID:D001943]
Hypotension
Orthostatic[MeSHID:D007024]
Migraine Disorders[MeSHID:D008881]
Degenerative polyarthritis[MeSHID:D010003]
Patent ductus arteriosus[MeSHID:D004374]
Dental Health Services[MeSHID:D003752]
Heart failure[MeSHID:D006333]
Lung[MeSHID:D008168]
Inflammation[MeSHID:D007249]
Parkinson Disease[MeSHID:D010300]
Descending aorta[MeSHID:D001013]
Arthritis[MeSHID:D001168]
Dysmenorrhea[MeSHID:D004412]
Chronic pain[MeSHID:D059350]
Blood Vessel[MeSHID:D001808]
Disease[MeSHID:D004194]
Headache[MeSHID:D006261]
Labor (Childbirth)[MeSHID:D007743]
Pulmonary artery structure[MeSHID:D011651]
Hypernatremia[MeSHID:D006955]
Rheumatism[MeSHID:D012216]
Toothache[MeSHID:D014098]
Birth[MeSHID:D036801]
Spondylitis[MeSHID:D013166]
neutrophil[MeSHID:D009504]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 0.32 approved inhibitor
ibuprofen protein s100-a7 small molecule NA drugbank Diuretic Effect[MeSHID:D004232]
Cystic Fibrosis[MeSHID:D003550]
Pregnancy
Prolonged[MeSHID:D011273]
Pain[MeSHID:D010146]
Platelet aggregation[MeSHID:D010974]
Psychological inhibition[MeSHID:D007266]
Pain
Postoperative[MeSHID:D010149]
Body tissue[MeSHID:D014024]
Rheumatoid Arthritis[MeSHID:D001172]
Tension Headache[MeSHID:D018781]
Fever[MeSHID:D005334]
Malignant neoplasm of breast[MeSHID:D001943]
Hypotension
Orthostatic[MeSHID:D007024]
Migraine Disorders[MeSHID:D008881]
Degenerative polyarthritis[MeSHID:D010003]
Patent ductus arteriosus[MeSHID:D004374]
Dental Health Services[MeSHID:D003752]
Heart failure[MeSHID:D006333]
Lung[MeSHID:D008168]
Inflammation[MeSHID:D007249]
Parkinson Disease[MeSHID:D010300]
Descending aorta[MeSHID:D001013]
Arthritis[MeSHID:D001168]
Dysmenorrhea[MeSHID:D004412]
Chronic pain[MeSHID:D059350]
Blood Vessel[MeSHID:D001808]
Disease[MeSHID:D004194]
Headache[MeSHID:D006261]
Labor (Childbirth)[MeSHID:D007743]
Pulmonary artery structure[MeSHID:D011651]
Hypernatremia[MeSHID:D006955]
Rheumatism[MeSHID:D012216]
Toothache[MeSHID:D014098]
Birth[MeSHID:D036801]
Spondylitis[MeSHID:D013166]
neutrophil[MeSHID:D009504]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved inducer
ibuprofen thrombomodulin small molecule NA drugbank Diuretic Effect[MeSHID:D004232]
Cystic Fibrosis[MeSHID:D003550]
Pregnancy
Prolonged[MeSHID:D011273]
Pain[MeSHID:D010146]
Platelet aggregation[MeSHID:D010974]
Psychological inhibition[MeSHID:D007266]
Pain
Postoperative[MeSHID:D010149]
Body tissue[MeSHID:D014024]
Rheumatoid Arthritis[MeSHID:D001172]
Tension Headache[MeSHID:D018781]
Fever[MeSHID:D005334]
Malignant neoplasm of breast[MeSHID:D001943]
Hypotension
Orthostatic[MeSHID:D007024]
Migraine Disorders[MeSHID:D008881]
Degenerative polyarthritis[MeSHID:D010003]
Patent ductus arteriosus[MeSHID:D004374]
Dental Health Services[MeSHID:D003752]
Heart failure[MeSHID:D006333]
Lung[MeSHID:D008168]
Inflammation[MeSHID:D007249]
Parkinson Disease[MeSHID:D010300]
Descending aorta[MeSHID:D001013]
Arthritis[MeSHID:D001168]
Dysmenorrhea[MeSHID:D004412]
Chronic pain[MeSHID:D059350]
Blood Vessel[MeSHID:D001808]
Disease[MeSHID:D004194]
Headache[MeSHID:D006261]
Labor (Childbirth)[MeSHID:D007743]
Pulmonary artery structure[MeSHID:D011651]
Hypernatremia[MeSHID:D006955]
Rheumatism[MeSHID:D012216]
Toothache[MeSHID:D014098]
Birth[MeSHID:D036801]
Spondylitis[MeSHID:D013166]
neutrophil[MeSHID:D009504]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]		 NA approved inducer
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