Drug-Target Information
Drug Name Target Name Drug Type Target Type Source Drug MeSHID Interaction Score Drug Status Target Action
tolazoline alpha-1a adrenergic receptor small molecule NA drugbank , DGIDB Pulmonary artery structure[MeSHID:D011651]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Pulmonary Hypertension[MeSHID:D006976]		 0.71 approved,vet_approved antagonist
tolazoline alpha-2a adrenergic receptor small molecule NA drugbank , DGIDB Pulmonary artery structure[MeSHID:D011651]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Pulmonary Hypertension[MeSHID:D006976]		 0.3 approved,vet_approved antagonist
tolazoline alpha-2b adrenergic receptor small molecule NA drugbank , DGIDB Pulmonary artery structure[MeSHID:D011651]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Pulmonary Hypertension[MeSHID:D006976]		 0.36 approved,vet_approved binder,antagonist
tolazoline alpha-2c adrenergic receptor small molecule NA drugbank , DGIDB Pulmonary artery structure[MeSHID:D011651]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Pulmonary Hypertension[MeSHID:D006976]		 0.31 approved,vet_approved binder,antagonist
tolazoline dopamine d2 receptor NA Successful target TTD , DGIDB Pulmonary artery structure[MeSHID:D011651]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Pulmonary Hypertension[MeSHID:D006976]		 0.07 approved unknown
tolazoline histamine h1 receptor small molecule NA drugbank Pulmonary artery structure[MeSHID:D011651]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Pulmonary Hypertension[MeSHID:D006976]		 NA approved,vet_approved agonist
tolazoline histamine h2 receptor small molecule NA drugbank Pulmonary artery structure[MeSHID:D011651]
Disruptive
Impulse Control
and Conduct Disorders[MeSHID:D007174]
Pulmonary Hypertension[MeSHID:D006976]		 NA approved,vet_approved agonist
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